208 resultaten
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
Addition of Partner for Change Outcome Management System (PCOMS) to individual treatment will result in a significant decrease of drop-out compared to individual treatment without PCOMS in a forensic outpatient clinic in the Netherlands. A sub-…
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
4 weeks of consumption of an infant formula containing milk fat reduces calcium soap formation compared to the reference formula.
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
Standing leads to better performance on cognitive tasks regarding executive functioning.
Ankle bracing has shown to be effective for the prevention of ankle injuries in athletes. However, the working mechanism of this preventive effect remains unclear. A contributing preventive factor of ankle braces mentioned in literature is enhanced…
We hypothesize that TRH effectively antagonize opioid-induced respiratory depression
Inhaled levodopa provides more rapid symptom relief than orally administered levodopa
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
We want to examine the effects of both the adjustable rocker profile and the self-adjusting insole on in-shoe pressure in this patient group. We expect to find similar reductions in pressure as previously found in healthy subjects. Also, the…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
The hypothesis is that the Manometric brace is superior to conventional plaster braces in terms of patient satisfaction, compliance and patient preference. For pain and hand function, no superior outcomes are expected for the Manometric brace…
human milk will phase separate and thereby empty differently from infant formula
Inadequate palliative care for elderly patients can result in unplanned hospitalisation, reduced quality of life and patients not dying at their place of preference. Barriers to appropriate palliative care can be found at the organisational,…
LRRK2 kinase inhibitors represent a new class of therapeutics with potential to address the underlying biology of Parkinson’s disease. LRRK2 activity is linked to a central mechanisms of Parkinson’s disease pathology through its role in lysosomal…
1) There will be an effect of anodal stimulation to the left STG with reduced response bias on the signal detection task 2) This effect is specific for speech signal detection.
the present study investigates whether Circadian adjusted LED-based (biodynamic) lighting improve cognitive functions, circadian rhytm, behavioral problems (apathy and agitation), Quality of life and mood (depression) in patiënts with moderate- to…