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The influence of shock wave therapy on function improvement of upper limb muscles after stroke.

Authors hypothesized that the physical extracorporeal shock wave (ESW) stimulation will decrease the resting muscle activity of paralysed forearm muscles, reducing the degree of spasticity in surface electromyography examination as well as Modified…

The MEtformin-LIfestyle in Antipsychotic users trial

We expect that metformin in combination with lifestyle interventions reduces Antipsychotic induced Weight Gain compared to placebo in combination with lifestyle interventions.

A Randomized, Double-blind, Placebo-controlled Trial on the Prevention of Chronic Postoperative Pain after Inguinal Hernia and Knee Surgery by Postoperative Treatment with Tapentadol

We hypothesize that treatment with Tapentadol will reduce the development of chronic postoperative pain by enhancing or maintaining CPM responses and possibly reducing central sensitization. We hypothesize that a 4-week treatment with Tapentadol…

A Phase II study to investigate the effect of Glivec® (imatinib mesylate, formerly known as STI571) in patients with inoperable medullary thyroid carcinoma.

In the pathogenesis of medullary thyroid carcinoma a mutation of the RET thyrosine kinase system plays an essential role. In animal models the thyrosine kinase inhibitor imatinib showed tumor regression. So a Phase-2 study in patients with…

GBA-PD Patient Imaging study of LTI-291 versus placebo.

Is CD35 Associated With Exudative Age-Related Macular Degeneration.

Is CD35, CD21, CD55 associated With Exudative Age-Related Macular Degeneration?

Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-61393215 in Healthy Participants

PK and PD effects of JNJ-61393215

Microneedling after reconstructive scarring

30% improvement is the minimal effect found in previous microneedling studies, based on this studies we expect to find a 7.5 point improvement on the POSAS total score

Delirium treatment at the surgical ward (DELTa S)
Treatment of delirium: rivastigmine or haloperidol as primary treatment for delirium in elderly patients with a fractured hip.
A randomized placebo-controlled study.

Rivastigmine is as effective in the treatment of delirium as Haloperidol.

Organ protection by noble gases – Helium induced Early and Late Preconditioning (HELP) in human endothelium.

Heliuminduces early and late preconditioning after regional ischemia of the arm.

Delirium treatment at the geriatric ward (DELTa G)
Treatment of delirium: rivastigmine or haloperidol as primary treatment for delirium in delirious patients on a geriatric ward.
A randomized placebo-controlled study.

Rivastigmine is as effective as haloperidol in the treatment of a delirium.