502 resultaten
Diabetes Mellitus type 1 is an autoimmune disease that cannot be cured. Complications due to insufficient regulation of blood glucose by exogenous insulin reduce life expectancy and quality of life. Proinsuline-loaded Tolerogenic DCs are induce…
By strengthening physiological awareness and supporting use of prevention skills, we suppose that biofeedback can aid to reduce aggressive behaviour. More specific, we expect the participating patients to show more insight in physiological stress…
We hypothesize that bronchoscopic/endosonographic (EBUS/ EUS-B) guided nCLE-imaging of lung tumors/ nodes followed by tissue sampling for the diagnosis and staging of lung cancer is feasible and safe.
To investigate the diagnostic value of the mannitol challenge test compared to the eosinophilic inflammation in the airways.
Primary research question: Does the amplitude of late SPN in the 500ms preceding a pain stimulus differ between the anticipation of moderate pain versus heightened, nocebo augmented pain, during the evocation of nocebo effects on pain? Primary…
To evaluate the clinical and diagnostic ability of the micro TEE transducer, the smallest multiplane TEE in the world, in pediatric patients greater than 2.5 kg undergoing cardiac surgery to provide data on imaging quality.
Platelet activity of patients with MAFLD after addition of antiplatelet drugs in vitro is similar to that of patients without MAFLD.
The objective of this study is to evaluate the biomechanical effect of the newly developed rocker soles aiming to reduce the mechanical load in patients suffering with Achilles tendinopathy and plantar fasciitis. A secondary objective is to evaluate…
To get insight in the long term results (mortality, morbidity and cardiologic function) of patients with congenital heart disease operated at young age. To compare whether the changes in surgical techniques have resulted in an increase of (…
This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.
The research project focuses on identifying early predictors (brain damage, cognition and behavior) for recovery after a SAH. The research also focuses on using advanced neuro-imaging for better mapping of (indicators of) brain damage after a SAH,…
Good clinical performance compared to literature
We hypothesize that direct SEMS placement in patients with unresectable primary malignant perihilar obstruction minimizes post-drainage cholangitis and mortality, requires fewer reinterventions, and increases the rate of patients receiving…
About 15% of the patients with gallstones detected by EUS will pass the stones spontaneously into the bowel. This means that in these 15% unnecessary ERCP can be avoided.
patients with diabetic cardiovascular autonomic neuropathy are more prone to hypotension during surgery and therefore require more inotropic/vaspressor medication perioperatively
We hypothesise that, within the group of low-risk disease the initial tumour volume and tumour growth assessed with HistoScanning would be a marker of disease progression.
In general we hypothesize that the characteristics of voice hearing in patients with schizophrenia spectrum disorders with a childhood trauma history are not significantly different from those in patients with a dissociative identity disorder,…
It is hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an increase of satiety sensation and therefore a decrease in food intake.