22 resultaten
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
PPIs are prescribed very frequently and might cause potentially severe hypomagnesaemia. We carried out a study focussing on the prevalence of hypomagnesaemia in geriatric inpatients using PPI and evaluated risk factors contributing to this effect.…
This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
To evaluate the safety and feasibility of performing conservative surgery in women with stage IA2 or IB1 carcinoma of the cervix with favorable pathologic features
The reported incidence of delirium in the intensive care unit varies from 16 to 89%. A delirium is associated with increased mortality, increased hospital length of stay, higher cost of care and cognitive impairment. The Pain, Agitation and Delirium…
In old age, sufficient protein intake is important to preserve muscle mass and function. Around 50% of older adults (65+ y) consumes ¡Ü1.0 g/kg adjusted body weight (BW)/day (d). There is no rapid method to screen for low protein intake in old age…
We investigate the effectiveness of a multidisciplinary treatment Resolutions Approach (RA) in families with alleged child abuse supplemented with the assessment form of Turnell (Turnell et al., 2009). We investigate the effects of RA on the primary…
Hypotheses are that the long-term supervision of the CooL intervention will be related to beneficial changes in the participants¡¯ energy-balance related behaviours, body composition, and quality of life. Besides, the goal of the intervention is to…
We hypothesize that percutaneous edge-to-edge mitral valve repair using MitraClip reduces left ventricular end diastolic volume and improves myocardial perfusion.
1) Several symptoms will not improve after removal. 2) Symptoms are similar to other tubal occlusion methods
Protein-energy malnutrition (PEM) is a major problem in older adults worldwide. Whether poor diet quality is an indicator for the long-term development of PEM is currently unknown. The aim of this study is to determine whether poor diet quality is…
WSI can equally to Conventional Light Microscopy (CLM) be used in primary diagnosics of cervical cytological thin-layer slides
Breast-conserving surgery followed by radiotherapy is a safe and effective procedure to treat early stage breast cancer. In many women, this type of treatment gives beside a good survival a good cosmetic result. However, some women will be troubled…
The aim of this study is to evaluate whether consulting a sexologist will have better outcomes considering quality of life and sexual function in women who underwent surgical treatment for (pre)malignant vulvar lesions.