97 resultaten
Does sildenafil improve tumour perfusion?
In each stratum of probability there is a clinically and statistacally significant difference in the functional ability and disease activity score over time (area under the curve) and progression of radiological joint damage after 1 year of follow-…
1. Cognitive behavioural group therapy is more effective than no intervention in prevention of social anxiety and related psychological problems; 2. Computer-based BiasRetraining is more effective than no intervention in prevention of social anxiety…
The use of parenterally administered LEV in neonatal epileptic seizures, detected electrographically, with or without clinical signs, will be safe, and pharmacokinetic and –dynamic properties of the use in neonates will be determined.
Therapeutic footwear of which adequate off-loading properties are guaranteed and monitored by dynamic plantar pressure assessment will result in a reduced plantar re-ulceration rate in diabetic patients with prior plantar foot ulceration compared to…
The measurements of overnight SpO2 and/or gas mixing and/or overnight cough might be useful in CF patients aged 0-4 years old. In this age group, standard spirometry can not (yet) be performed. As a consequence, there currently are no measurements…
Lapatinib inhibits the function of Cytochrome P450 3A isoforms and P glycoprotein.
The primary aim of our study was to test the feasibility and safety of exclusively intramuscular, and combined intramuscular/intra-arterial delivery of Bone marrow Mononuclear Cells (BMC) in patients with advanced without conventional options for…
Brachytherapy is globally used as a primary treatment for prostate cancer. The advantage of brachytherapy is that the radiation dose on healthy organs can be limited. Because prostate cancer is a multifocal disease the whole prostate has to be…
The hypothesis of the present study is to demonstrate that detection of a particular pattern (e.g., persistent vs. non-persistent) of myocardial (alpha)V(beta)3/5 expression by scintigraphy imaging at 3 and 8 weeks after MI can be used to determine…
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
An active revascularization strategy, i.e. recanalization of a CTO, might improve function in non-infarcted hibernating myocardium and promote infarct healing at the border zones. These effects may attenuate the remodeling process, which may lead to…
HbA1c can improve in type 1 diabetes patients who continuously use the Paradigm® REAL-Time system.
The age-specific seroprevalence of a cross-section of the Dutch population for the vaccinations used in the Dutch National Immunisation Programme.
Subcutaneous immunoglobuline therapy is as effective as intravenous immunoglobuline therapy in maintaining muscle strength in patients with multifocal motor neuropathy
Treatment with Infliximab will reduce loss of visual acuity by 8 letters or better on the ETDRS chart.
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
Intraneural injection of anesthetics in upper and lower extremity blocks increases the risk of neurological damage.
It is generally accepted that the early-postoperative flow increase is indicative for successful maturation of an autologous arteriovenous fistula. Our hypothesis is that a patient-specific computer simulation model should be able to predict this…
Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care. In patients with shortness of breath due to heart failure increased plasma levels of…