225 resultaten
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
Radium-223 is the 5th treatment for metastasized castration resistant prostate cancer with a proven overall survival benefit. The improved survival of Radium-223 over placebo was demonstrated in the ALSYMPCA trial, which included a miscellaneous…
The primary objective of this study is to explore the correlation between invasive and non-invasive haemodynamic variables and monitor the effect of treatment during admission for acute decompensated heart failure. In particular to investigate…
It will be investigated whether passive leg raising and stroke volume variations can be used in predicting renal responses to fluid administration. Our hypothesis is that dynamic predictors of cardiac fluid responsiveness can predict an increase in…
The Maastricht brace is a new develwoped thoracolumbar brace that improves wearability and quality of life, while maintaining efficiency and function
Self monitoring of the ECG by the patient contributes to the correct diagnosis, reduces the frequency of cardiology consultations and leads to less side effects and lower dosage of medication. Patients become more confident and gain more insight…
Children hospitalized with a lower respiratory tract infection have a different NP microbiome composition compared to healthy children.
We hypothesize that offering patient after general surgery water ice cream will reduce the side effects of sore throat and foul smell and in general increase the quality of recovery.
Anti-TNF treatment (infliximab (IFX), adalimumab (ADA)) has become standard therapy for refractory pediatric and adult Crohn¡¯s disease (CD) patients, and is used for the induction and maintenance of remission. When effective, clinical and…
increased gastric distention will induce greater activation in satiety related areas
Patients subject to MET review have a high in-hospital mortality (20%). Thus, understanding the outcome of patients within the first 24hr of MET review is important in developing quality improvement and interventional studies to reduce this…
The one-dimensional personalized pressure model is able to predict the pressure drop over stenotic lessions in the common and external iliac arteries.
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
Objective: The overall aim of this project is to asses the prognostic value of the characteristics of an echocardiographic surrogate pressure-volume loop on mortality and morbidity due to PAH.
The EuraHS-QoL questionnaire is a valid instrument to measure quality-of-life before and after ventral hernia repair.
Refinement of the CHIP prediction rule will lead to a more efficient use of head CT in patients with minor head injury
To use the GSV for bypass surgery it is of the utmost importance to subtract the vein with as limited damage as possible. To harvest the GSV three techniques are generally used, namely; Standard reversed technique using additional incisions in the…
We hypothesize that the active strategy leads to a better functional outcome than the conservative strategy three months after acute ischemic stroke, in patients with elevated pre-treatmen blood pressure otherwise eligible for intravenous…