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We hypothesize that clinicians exposed to this intervention are more likely to adopt SDM behaviors than clinicians who do not. A secondary aim is to evaluate whether patients perceive more involvement in the decision-making process.
3D printed tailormade assistive aids may better fulfill the requirements and needs of clients with disabilities to support them in performing their activities of daily living than the currently available aids or handmade aids provided by…
The aims of this study are validation of PROMs and estimating the minimal important change (MIC) for PROMs and CROs.
Organoids can be cultured from pancreatic ductal biopsies, obtained from chronic pancreatitis patients, to study electrolyte and fluid secretion.
Primary Objective: • To create a population pharmacokinetic model of SARS-COV-2 neutralizing antibodies as present in ConvP. • To create a population pharmacokinetic model of SARS-COV-2 neutralizing antibodies as present in Nanogam plus Secondary…
Participant demographics affect the health state. TPO-RA treatment affects the severity of symptoms, overall health condition, health state, overall satisfaction with therapy and reasons for discontinuation. TPO-RA treatment affects direct…
COMET measurements are feasible in patients with PAOD and the measurements are tolerable.
1. Disability & Quality of life (descriptive nature, primary analyses) Change in patient-reported outcome variables in overall group (MS diagnosis) and subgroups (CIS, RRMS, SPMS, PPMS) from baseline to 8-year follow-up • Change in…
Transcutaneous blood gas measurements can be used to detect neonatal sepsis.
Lung transplantation patients are immunocompromised due to antirejection therapy. The effectivity of the COVID-19 vaccination in this high-risk patient group is completely unknown.
The main endpoint will be successful sampling and storage of testicular tissue (that is 75% of the samples to be stored for future stem cell preservation will have germ cells). This can be identified based on histological analyses (immuno-),…
none applicable
helicopter transport can be done safe without changes in vital signs
The hypothesis is that methylation marker panel, potentially combined with additional biomarkers, can predict (non-)regression of HGAIN, thus determining the need of immediate treatment versus active surveillance, and the safety of withholding…
We expect an increase in the number of hospitals that have implemented and use a cognitive aid in the OR compared to the number of hospitals in 2018
The primary hypothesis is that local antibiotics are a safe treatment option in the prevention and treatment of fracture-related infections, achieving higher local concentrations without the potential adverse events associated with systemic…
Sex differences in renal physiology is a vastly understudied area, despite known differences in sex-specific rates of chronic kidney disease. Renal function decline is accelerated in men compared to women, suggesting a potential harmful role for…
From survey studies it is suggested that patient preference and satisfaction will be in favour of oral JAK inhibitors over parenteral biologics. 5,6,7 We want to establish the treatment preference of patients with active RA and compare the treatment…
The analysis of protease activity from saliva and the salivary biofilm, using these substrates, may provide a new layer of information useful in the discovery of prognostic markers with respect and related to the histopathological features of oral…
We aim to compare the accuracy of ultrasound derived blood flow parameters from the carotid artery to pulse-contour derived cardiac output and non-invasive cardiac output measurements. Our motivation is to develop a non-invasive, radiation-free,…