54 resultaten
Objectives Primary: To examine the effects of regular glucose lowering treatment on inflammatory markers in type 2 Diabetes Mellitus Secondary: To identify markers/fingerprints that predict the response of a patient to glucose lowering therapy in…
we would like to investigate whether multiple fecal transplantations using either allogenic (lean preferably vegetarian/vegan donor) or autologous (own) donors have a beneficial effect on non alcoholic steatohepatitis (NASH) using biopsy and MRI…
In this observation study we hypothise an incidence of UTIs of 30% in the first year after starting CIC. Moreover we hypothise a marked reduction in quality of life and an increase in health care expensis in patients with UTI.
The maternal diet is highly responsible for the composition of breast milk which will result in at least differences between cultures and geographical separated populations. The maternal diet and breastmilk composition will show off in the…
Microspirometry result in a higher proportion of diagnostic spirometric assessment to objectify the existence or absence of a chronic airflow obstruction within 3 months after a patients at risk for COPD visited the GP compared to usual care.
The primary objectives of this project are: - Identify neural correlates and behavioural measures that underlie cognitive processes that perpetuate CFS symptoms - Identify neural mechanisms of change that mediate successful CBT.
This study will explore the feasibility of post-transplant panobinostat combined with decitabine after reduced intensity conditioning (RIC) alloHSCT in patients with (very) poor-risk AMLor RAEB with IPSS >= 1.5 (AML/RAEB). While recent…
“Personalized Prevention Approach for CardioMetabolic Risk” (PPA CMR), a prevention program for cardiometabolic disease (CMD) combined with an individualized lifestyle intervention, is effectiveness and cost-effectiveness when implemented in primary…
In Gabon, antimalarial drugs are widely available in both the private as well in the public sector and often self-prescribed (correctly and incorrectly) for the many febrile episodes attributed to malaria. Insufficient facilities to check the…
The introduction of ultrasound will give reduction of at least 25% in radiation burden on healthcare professionals in the pain clinic
The hypothesis is that immunization against VEGF will circumvent the specific drawbacks of the current anti-VEGF treatment modalities. The primary objectives of this study are to investigate the safety and tolerability of hVEGF26-104/RFASE and to…
18F-FDHT PET/CT is expected to be a predictor of response in patients with metastasized castration-resistant prostate cancer to be treated with enzalutamide
This is a clinical trial in the home environment of 60 epilepsy patients to investigate the sensitivity and positive predictive value of a multimodal sensor system (‘LivAssured’) for the detection of nocturnal motor seizures.
The aim of the study is: (1) observational, i.e., to assess and describe the responses of patients and volunteers to a variety of different stimulation paradigms; (2) diagnostic, i.e., to assess whether specific tests are possibly diagnostic for…
The percentage of successful PIV insertions at the first attempt in newborns will increase with the Veinviewer® and/or Astodia®, two vascular imaging devices
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy with an acceptable toxicity profile.
To find out if intravenous MSC is a safe treatment for children with therapy-resistant JIA
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Bipolar radiofrequency lesioning of the thoracic medial branch of the dorsal ramus is more effective than a monopolar radiofrequency lesion
The present study aims at the improvement of the treatment of children with PTSD by examining the effectiveness of a brief intensive exposure therapy (IET) for children with PTSD using a multiple baseline design (patients are randomly assigned to…