184 resultaten
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
The Untire app will create awareness by proving psycho-education and will give insight in ones’ energy levels, ones’ thoughts and behaviors in relation to energy levels and provides exercises that help users to challenge ineffective thoughts and…
The aim is to examine the natural course of Acute Stress Disorder (ASD) symptoms (aim 1) and the effects of these symptoms on the development of Port-Traumatic Stress Disorder (PTSD) and patients¡¯ psychological distress (i.e., anxiety and…
To investigate the possibility to predict chemotherapy response using proliferation assays.
With help of the TOF watch, a reduction in muscle relaxation can be observed earlier. In this way, peroperative events (pain or contractions by the patient) can be prevented. Less peroperative events lead to less postoperative pain.
A decline of intra-tumoral concentrations over time could be the first sign of the development of drug resistance by the tumor. In this exploratory study we will investigate the relationship between plasma and intra-tumoral paclitaxel concentrations…
The aim of this study is to develop and validate an age-specific checklist that can help clinicians to identify elderly patients with personality disorders in need of highly specialized mental health care.
The manual knee-rotation-test in 90 degree flection is reliable
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
An early mobilization program in critically ill children reduce the consumption of sedatives and opioids and the prevalence of delirium.
We hypothesize that the range of motion of the hallux is limited during gait in patients with hallux rigidus (HR). In addition, we hypothesize that patients with HR will compensate this loss of motion of the hallux by increasing joint motion in the…
We hypothesize that providing personalized feedback on one’s health and diet will help low socio-economic status consumers to improve their dietary pattern, and even more so if personalized dietary advice is added to the feedback. The pilot study…
Remote patient reported outcome measures (replacing partial Mayo) can be used for monitoring continuous clinical control of UC disease
We expect that the older patients with SMI have more somatic health problems, disorders and complaints, compared to the adult patients with SMI.
Combining factors will enable prediction of successful long-term video-EEG monitoring and of adverse effects, related to antiepileptic drug withdrawal.
Epidral analgesia has superior pain management outcomes. On the other hand we hypothize EA requires more aggressive hemodynamic support, leading to higher risk of postoperative complications.
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…