219 resultaten
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery
1. A higher resting and funtional PFM activity is observed in more distal areas from the introitus of the vagina. 2. A higher resting and funtional PFM activity is observed on the anterior wall of the vagina
To test the hypothesis that observing the data and waveforms displayed on an respiratory function monitor during the provision of positive pressure ventilation to preterm infants at birth will increase the proportion of tidal volumes within a…
Use of exercise instructions by means of a tablet and monitoring by means of a necklace-worn motion sensor is beneficial for adherence in home-based exercise programs for older adults.
Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume both in obese and diabetic subjects; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment…
The carotid artery reactivity-test will have independent prognostic value compared to the current, standard prognostic tests (i.e. ankle-brachial-index, walking distance) for patients with peripheral artery disease
Focusing on disease-modifying rather than etiologic mechanisms may accelerate the development of novel therapies and complement current research initiatives on causative mechanisms and curative therapies.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
Different prevention strategies are used internationally to prevent Early-onset Group B haemolytic streptococcus infection (EOGBS). However, none of the preventive EOGBS strategies in place at present result in the complete prevention of EOGBS,…
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
The primary objective of this study is to determine whether thrombectomy combined with ischemic postconditioning after PCI leads to a smaller myocardial infarction compared to standard therapy.
The purpose of this research is to acquire a better understanding of the pain experience and the recovery of children between 1.5 and 5 years old who underwent a tonsillectomy/adenotonsillectomy. Primary research question: What is the influence of…
The national quality improvement program palliative care will improve quality of palliative care on a national level and the separate trajectories implementing ‘good practices’ will improve quality of palliative care on the regional and…
There is no difference between CT- and MRI-based Patient specific matched instruments for total knee arthroplasty
Application of the SeMaS questionnaire and subsequent personalized self management support will be more effective in enhancing patients’ self management behaviors than care as usual.
We hypothesize that multidisciplinary team training, to support implementation of a structured referral between obstetrical professionals, will result in better collaboration and thereby to a decrease in adverse perinatal outcomes
The aim of this phase I study is to assess the extent of intestinal absorption of rivaroxaban and dabigatran etexilate in adult patients with short bowel syndrome requiring long-term TPN.
Liver and adipose tissue levels as well as serum levels of RBP4 are higher in obese subjects compared to lean subjects. In obese subjects tissue and serum levels of RPB4 are correlated with insulin sensitivity and hepatic triglyceride content.
thrombocyte function recovers quickly after cardiopulmonary bypass.
Roux-en-Y Bariatric (RYGB) surgery is a successful approach to morbid obesity. In this procedure, the stomach is reduced to a small 'gastric pouch' . The duodenum is bypassed by connecting the jejunum this gastric pouch. The duodenum is…