219 resultaten
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery
Primary Objective: • Is CBM-I successful in changing the cognitive bias in patients with cluster-C personality disorders or personality disorder NOS? Secondary Objective(s): • Will patients following CBM-I show a significant reduction in symptoms…
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.
Child maltreatment is a major social problem with many adverse consequences. A substantial number of maltreated children is not identified by health care professionals. To improve identification of maltreated children in hospitals, a new hospital-…
To reduce treatment-related toxicity in patients with localized prostate cancer, focal treatment is warranted. This can be achieved with MRI guided high-dose-rate brachytherapy. We expect that a single dose of 19 Gy to the tumour volume will be of…
Recent pre-clinical experiments demonstrated that sorafenib in Oatp1b2(-/-) mice had 8-fold increased sorafenib-glucuronide blood concentrations.OATP1B1 and 1B3 are highly expressed in the human liver and facilitate the hepatocellular uptake of…
The primary objective of this study is to determine whether thrombectomy combined with ischemic postconditioning after PCI leads to a smaller myocardial infarction compared to standard therapy.
The purpose of this research is to acquire a better understanding of the pain experience and the recovery of children between 1.5 and 5 years old who underwent a tonsillectomy/adenotonsillectomy. Primary research question: What is the influence of…
The national quality improvement program palliative care will improve quality of palliative care on a national level and the separate trajectories implementing ‘good practices’ will improve quality of palliative care on the regional and…
There is no difference between CT- and MRI-based Patient specific matched instruments for total knee arthroplasty
Het onderzoek is gericht op het vaststellen van factoren die betrokken zijn bij subfertiliteit en ernstige zwangerschapscomplicaties die in het begin van de zwangerschap ontstaan. Door toename aan inzicht in de pathogenese van deze aandoeningen, zou…
Spinal anesthesia induces several alterations in normal brain processes. Firstly, loss of afferent information increases pain sensitivity. In our previous study on the effects of spinal anesthesia (P11.221) we showed that subjects felt more pain…
Application of the SeMaS questionnaire and subsequent personalized self management support will be more effective in enhancing patients’ self management behaviors than care as usual.
We hypothesize that multidisciplinary team training, to support implementation of a structured referral between obstetrical professionals, will result in better collaboration and thereby to a decrease in adverse perinatal outcomes
Augmentation of the maxilla with calvarial bone has a lower complication rate than iliac crest bone.
N/A
The aim of this study is to evaluate the efficacy, and feasibility of the Absorb bioresorbable scaffold in infrapopliteal hemodynamically significant arterial stenoses and occlusions.
Roux-en-Y Bariatric (RYGB) surgery is a successful approach to morbid obesity. In this procedure, the stomach is reduced to a small 'gastric pouch' . The duodenum is bypassed by connecting the jejunum this gastric pouch. The duodenum is…
An impaired barrier function of the oesophageal epithelium plays a role in the pathophysiology of EoO, enabling passage of molecules with the size of food allergens through the epithelium and possibly causing immune activation. Since most EoO…