222 resultaten
Effect of beta 3 receptor agonist on urethral pressure variations during urodynamic investigation
Current clinical practice is to perform response evaluation, i.e. examination under general anesthesia (EUA), routinely at 3 months after the end of treatment in patients who underwent chemoradiation for oropharyngeal cancer. Due the high response…
Submucous fibroids are known to be related to heavy menstrual bleeding (HMB), dysmenorrhea and fertility problems. Transcervical resection of fibroids (TCRM) is a widely implemented treatment for submucous fibroids, to be precise FIGO PALM-COEIN…
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
The purpose of this clinical investigation is to evaluate the accuracy of the Senseonics Continuous Glucose Monitoring System (Senseonics CGM System) measurements when compared with reference standard measurements (YSI glucose analyzer). The…
The sentinel lymph nodes (SLN) are the first lymph nodes to drain the tumor site and therefore the first lymph nodes to bare metastases. Hence the importance to investigate these lymph nodes to define the best treatment strategy. Currently in a.o.…
Our hypothesis is that changes in (phospho)proteomic and kinase activity profiles in tissue before and after treatment with PKIs should provide more insight into which differential markers can be clinically used to predict response to this type of…
Previous or persisting infection with Chlamydia is associated with perinatal biliary atresia
Fentanyl is a strong opioïd and is highly lipophilic. Fentanyl pharmacokinetics are characterised by large inter- and inpatient differences, which may have serious consequences for the activity and toxicity profile of this drug. In this study we…
Magnetic resonance imaging (MRI) is now the imaging modality of choice for many neurological and musculoskeletal conditions. In the past, implanted cardiac devices including pacemakers (PM) have been contraindicated by MRI scanner, due to the…
There is consensus that an endotracheal intubation procedure should be performed while the infant is adequately sedated. However, whether sedation should be given during the minimal invasive surfactant procedure is still unclear. So far, no studies…
Care Sport Connectors (CSC) are employed to connect primary care, sport, and physical activity and to guide primary care patients on lifestyle programmes towards local physical activity facilities. The hypothesis is that the work of a CSC will lead…
T2DM patient supported by PRISMA training will result in an increased usage of a web portal (with patient’s self-management goals and information needs), improved participation of the patient in consultations with his health care provider and…
A personalized in vitro drug profiling method will allow a better prediction of responses and reduce unnecessary treatment toxicity.
Variations in pharmacogenetics and or pharmacogenetics are related to clinical outcome of treatment with strong-acting opioids for cancer-related pain
The primary goal of this observational case series study is to access the changes in health status of pain patients following on acupuncture treatment. Changes will be measured by the ‘MYMOP2-online’ questionnaire. Health status is defined as the…
The strategy of pessary as initial therapy is as effective as direct surgery for moderate to severe POP, but it is associated with lower costs.
We hypothesize that diagnostic accuracy increases when, apart from cytologic samples, material is aspirated for thin layer preparation in endoscopic-ultrasound guided fine needle aspiration (EUS-FNA) of masses.
Wait and see policy is a suitable approach for selected patients with aggressive fibromatosis.
Prophylactic radiological interventions do prevent major obstetric haemorrhage in patients at high risk of abnormally invasive placenta