168 resultaten
Patients could be stratified into a high-risk or a low-risk group so surveillance intervals can be tailored and the clinical and economic burden of endoscopic surveillance can be reduced.
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.
We hypothesize that OCD patients show confidence abnormalities: specifically decreased levels of confidence. We expect this to be exaggerated in symptom-specific contexts. Moreover, we hypothesize that the coupling between learning and confidence is…
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
Hypothesis 1: Refractory epilepsy patients will report a significant increase in quality of life, one and two years after ANT DBS or VNS treatment. Hypothesis 2: Refractory epilepsy patients will report a significant seizure frequency reduction…
Compared to SQUID-based MEG, OPMs are more sensitive to epileptiform activity from deeper brain stuctures, and in children. OPMs can also succesfully record seizure activity.
General anesthesia disturbs circadian rhythm in patients undergoing surgery, with effects being influenced by a person’s chronotype and the time of the procedure relative to the patients internal clock
Primary Objective: Our first aim is to quantify dopaminergic function in mesolimbic/mesocortical dopaminergic pathways (measured with 18F-FE-PE2I PET) in PD-depression with or without anhedonia. We hypothesize that lower DAT-availability (i.e. more…
We hypothesize that IOLA-ICG determined hypoperfusion in patients who develop a PCF or wound complications within 4 weeks after operation.
This will be a snapshot study, this is an hypotheses-generating design, without restraining to many in- or exclusion criteria. Thereby, this design generates a population-based overview, which rapidly provides insight in current clinical practice on…
Comparing the tumor tissue of patients with a breast cancer relapse to the tumor tissue of their primary breast cancer may help to identify mechanisms that are responsible for the relapse after exposure to anticancer agents, and thus further our…
We hypothesize that with this new stable isotope dilution method we will be able to assess the bioequivalence of dietary pro-vitamin A intake in future studies.
We hypothesize that treatment with voxelotor will result in lower blood viscosity, lower CBF and a restored CVR.
We expect to gain a more recent insight into the current disease burden of the IMD. This information can provide very valuable information for the influence of the disease on the Dutch population.
High BMI is associated with worst prognosis after SARS-CoV2 infection
The functional architecture of the cerebral network controlling breathing is impaired in patients with myotonic dystrophy type I.
Primary endpoint: Validate the VBMEG algorithm using hd-EEG source reconstruction compared to fMRI activity.
Setting up a nationwide, interdisciplinary platform for ovarian cancer research, including a biobank, will contribute to enhanced collaboration in fundamental and translational research • between disciplines; • between Dutch hospitals; •…
The aim is to register standard and enhanced peri-operative care and determine anastomotic integrity separately for both cohorts.