4945 resultaten
We hypothesize that restoration of gut microbiota diversity (by using donor FMT enriched in Desulfovibrio strains) could have explicit beneficial effects on glucose metabolism and NAFLD (via improved fructose catabolism), which is driven by…
Het effect onderzoeken van acute verhoging van groeihormoon waardes op cognitief functioneren in gezonde mensen, en uitvinden of de relatie tussen groeihormoon en cognitie direct of indirect is. Doel van het onderzoek: We willen de acute effecten…
Higher doses of statins will result in additional improvement of the diabetic lipid profile.
1: Blockade of the angiotensin II AT1-receptor improves the insulin-induced microvascular effects in hypertensive patients. 2: Blockade of the angiotensin II AT1-receptor impairs the insulin-induced microvascular effects in normotensive control…
Prednisone inhibits progression of joint damage in early RA-patients, even when intensive treatment, according to a strict computer-assisted protocol, is applied.
We hypothesize that methylphenidate improves ADHD manifestations in adults with (late-diagnosed) PKU.
The study objective is to show that Bifidobacterium animalis is effective in increasing defecation frequency after 3 weeks of product consumption in children with functional constipation.
Divergent Low Level Laser Therapy as novel treatment for oral mucositis in pediatric cancer patients
What is the effect of divergent LLLT on the number of days of mucositis > grade 1?
Augmentation of the contralateral hip in patients with a low energy hip fracture over 50Y willdecrease the change of a new hip fracture on the augemented side.
Vitamin K2 can increase the carboxylation of the Matrix-Gla-Protein.
Microalbuminuria in diabetes mellitus is not only associated with progression to renal disease, it is also a potent predictor of cardiovascular disease and thus may reflect widespread vascular damage. Endothelial dysfunction is one of the first…
The primary aim is to determine if there is a difference between tibolone and placebo or if there is a difference between raloxifene and placebo. The secondary aim is to determine if there is a difference between tibolone and raloxifene. Primary…
Part 1: To determine the respiratory response of low and high doses of GAL-021 in conjunction with a low dose of opioids and hypercapnia in healthy subjects. Part 2: To determine the respiratory response of low and high doses of GAL-021 in…
rTMS has a positive effect in the treatment of depression.
Long-chain triglyceride (LCT) emulsions with di-unsaturated fatty acids will lead to enhanced postprandial satiety and reduced energy intake in a subsequent meal, as compared to LCT emulsions with mono-unsaturated or saturated fatty acids.
We tested, in a randomized, double-blind, placebo-controlled trial, the effects of duloxetine on pain relief, tolerability, health status, and quality of life in patients with central neuropathic pain.
The hypothesis is that MS is a T cell-mediated autoimmune demyelinating disease of the central nervous system (CNS). In order to start immune reactions in the CNS, myelin antigen need to be presented on the surface of antigen presenting cells (APCs…
Asthma reduction at age 6 is possible with inhaled corticosteroids in children of 1-4.5 years old with a familial predisposition for asthma in the first degree, who develop wheeze symptoms.
Accumulating data in the literature support an important role for serotonin, in the neurobiology of CFS. Neuroendocrin and neuropharmacological studies point to an up-regulated or hyperresponsive serotonin system. Positive reports of the use of…
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that alters cortical excitability. A recent study in anaesthetized cats showed that tDCS also facilitates subcortical neurons. Here, we hypothesize that…