4945 resultaten
Prevention of type 2 diabetes (T2D) in high-risk individuals has been proven to be possible, as demonstated e.g. by the SLIM-, DPP- and DPS- studies. Intervention to achieve lifestyle adjustments appears to be effective in reducing the risk factors…
Find the best predictive biomarker for respons to treatment.
Simvastatin can have a positive effect on cognitive function and daily life functioning in children with Neurofibromatosis 1.
High-Volume Image-Guided injections will provide a significant improvement in symptoms compared to Low- Volume Image-Guided injections in patients suffering from chronic midportion Achilles tendinopathy
Doxepin hydrochloride 5% cream significantly reduces pruritus in burn patients in comparison with a placebo cream
Insomnia patients form a heterogeneous group, each phenotypes of insomnia will show different therapeutic demands.
Driving performance after administration of zopiclone 7.5 mg is not different between patients complaining of insomnia and frequently using hypnotics, insomnia patients not frequently using hypnotics and matched healthy controls.
Rosiglitazone results in an improvement in insulin sensitivity at the level of the liver as well as peripherally. In addition disturbances in fat distribution could improve, especially in this specific group of patients, who do not use d4T nor a…
Study will demonstrate the preventive effect of a new probiotic strain on mastitis in healthy breastfeeding women.
The average VISA-A score is higher in the patient group treated with eccentric exercise therapy in combination with a PRP injection in comparison with the group treated with a saline injection in combination with eccentric exercises.
1. H0= Placebo is inferior to sodium bicarbonate in the prevention of contrast induced nephropathy in patients undergoing CTPA; 2. H1=Placebo is noninferior to sodium bicarbonate in the prevention of contrast induced nephropathy in patients…
Antimicrobial therapeutic clothing are more effective in reducing the severity of atopic dermatitis than non-antimicrobial therapeutic clothing
Patients with ALS are routinely prescribed riluzole, the only registered drug for the treatment of ALS. This study will evaluate the concentration-effect relationship of riluzole (100 mg) and retigabine (300 mg) on axonal excitability measures. In…
If COMET increases the saliency of positive autobiographical memories, then memories that are activated during COMET (relative to no intervention control) should show an increase over time on all primary outcome measures, irrespective of medication…
It is hypothesized that Ziverel tackles esophageal hypersensitivity by protecting the mucosal barrier function.
We believe that self-management can be a (cost) effective way to improve patients’ ability to cope with their disease which can result, among others, in improved self-efficacy, adherence, and disease specific and generic quality of life.
1. We hypothesize that children with solitary encopresis have a disturbed compensation reflex, eventually combined with aberrant huge rectal contractions; 2. We hypothesize that in children with solitary encopresis loperamide rectally given, will…
A randomized double blind placebo controlled trial for the use of intravenous immunoglobulin to reduce the number of exchange transfusions in Rhesus disease of the neonate.
- Video observation of chewing during lunchtime has a beneficial effect on masticatory ability in older adults with dementia - Video observation of chewing during lunchtime has a beneficial effect on food intake, cognition, activities of daily…
Systemic eosinophilic inflammation in airway disease (asthma/COPD/asthma-COPD-overlap-syndrome (ACOS)) is associated with small airway inflammation manifesting in dynamic hyperinflation and specific symptoms, which can be reduced by systemic anti-…