285 resultaten
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
Therapeutic ultrasound will be more effective than placebo ultrasound at reducing pain and improving function in chronic low back pain patients.
S(+)-ketamine influences resting state fMRI in a dose-dependent fashion.
The aim of this study is to determine the safety and efficacy of intramyocardial injection of autologous bone marrow cells in no-option patients with severe ischemic heart failure.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
Topiramate leads to reduced olanzapine-induced weight gain and calory intake .
Is the application of CryoSeal (CS) by primary total knee replacement surgery beneficial for the patient with respect to a faster track and improved early (2 and 6 weeks) postoperative rehabilitation as determined by improved knee extension.
Postprandial hyperglycemia has a negative effect on aortic elasticity in patients with impaired fasting glucose versus matched controls.
In the present study we will investigate the efficacy of Lybrido and Lybridos in one group of subjects with FSD using SSRIs in the laboratory and in the domestic setting of these subjects. We will measure subjective, physiological and…
We hypothesize that treatment of patients with acute ischemic or hemorrhagic stroke and a body temperature of 36,5°C or above with paracetamol in a daily dose of 6 g for three consecutive days, leads to improved functional outcome. At least 50% of…
Dietary management with the medical food under study has a positive effect on muscle strength and physical functioning in elderly.
BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
Type 2 diabetes patients frequently suffer from physical deconditioning and vascular disease. Although the exact mechanisms are unclear, microvascular changes and endothelial dysfunction appear to inhibit the oxygen transport and uptake in…
31-3-2014 Hypothesis: Early administration of 5 mg of Metoprolol is associated with a relative 20% reduction in infarct size as measured by cardiac Troponin-T, a total of 408 patients will be enrolled and randomized. Interventions: 5 mg intravenous…
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This present study is a pharmacodynamic study of which the main goal is to confirm the lack of effect of testosterone sublingual alone in 16 premenopausal sexually dysfunctional healthy women using physiological and subjective measures of sexual…
HIV-induced immune activation through intestinal bacterial translocation can be modulated by statins.
Prolonged antibiotic treatment of patients diagnosed with presumed PLD (as endorsed by the international ILADS guidelines) leads to better patient outcome than short-term treatment as endorsed by the Dutch CBO guidelines.
We hypothesize that treatment with a DPP-4 inhibitor will enhance the glucagon response to hypoglycaemia in patients with type 1 diabetes.