57 resultaten
The tested intervention (level 5 intervention of Triple P, an intensive individual training for the family of children with behavioural problems) will cause a decrease in behavioural problems in children, dysfunctional parenting styles in parents,…
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
Approximately 1/3 of persons with IGT develops type 2 diabetes mellitus in 5-10 years time. Acarbose is an alpha-glucosidase inhibitor decreasing post-prandial glucose levels, without the risk of hypoglycemia. The prevention of diabetes with…
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
The module “Working with parents in creating a pleasant school” positively effects the attitudes, efforts and self-efficacy of teachers, parents, students in (jointly) counteracting bullying.
Actively providing patients with subdivided and interactive information after discharge from the hospital leads to increased self management, satisfaction and sense of involvement.
To assess the safety and tolerability of intravenous (IV) infusion doses and infusion dosing methodologies of ABP-700 alone or in the presence of pre-medications commonly used in the monitored anesthesia care (MAC) setting
College years are considered to be a peak period for the first onset of common mental disorders. Recent studies have shown that 12 to 50% of university students experience one or multiple psychological symptoms. Mental health is associated with…
We expect youth in the intervention group to show greater improvements in change beliefs, empowerment, coping and self-worth and greater reductions internalizing and externalizing problems in comparison to youth in the control group.
A bounding exercise programme is effective in preventing hamstring injuries in male amateur soccer players and has a good compliance
To evaluate if topical corticosteroid plus emollient cream is efficacious as topical corticosteroid applied twice daily in mild to moderate plaque psoriasis
Many interventions have been developed and implemented to tackle childhood obesity, but the most affected group of children – i.e. from families with a low Socio-Economic-Status (SES) and from non-Western backgrounds - is difficult to reach.…
•To investigate the safety and tolerability of multiple ascending oral doses of DNL104 in healthy subjects •To characterize the pharmacokinetics (PK) of DNL104 in plasma and measure the trough concentrations of DNL104 in CSF. •To Explore the…
1. The TrailS6 intervention will be effective on changing running training and general conditioning exercise behaviours towards to running injury prevention; 2. The TrailS6 intervention will be effective on reducing the prevalence of running…
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
Assess the safety and tolerability of single ascending IV bolus doses of ABP-700