39 resultaten
The TENLEP Trials proposal builds on the findings of the INFIR Cohort Study and the recommendations of the NLR-funded international Workshop on Neuropathology in Leprosy in the Netherlands in 2007. At this workshop, several key research questions…
Based on its general pro-hemostatic potential, prothrombin complex concentrate may be effective in (completely or partially) reversing the anticoagulant effect of the new antithrombotic agents Dabigatran and Rivaroxaban.
Therapeutic ultrasound will be more effective than placebo ultrasound at reducing pain and improving function in chronic low back pain patients.
Dietary management with the medical food under study has a positive effect on muscle strength and physical functioning in elderly.
We hypothesize that treatment of patients with acute ischemic or hemorrhagic stroke and a body temperature of 36,5°C or above with paracetamol in a daily dose of 6 g for three consecutive days, leads to improved functional outcome. At least 50% of…
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S(+)-ketamine influences resting state fMRI in a dose-dependent fashion.
Topiramate leads to reduced olanzapine-induced weight gain and calory intake .
This present study is a pharmacodynamic study of which the main goal is to confirm the lack of effect of testosterone sublingual alone in 16 premenopausal sexually dysfunctional healthy women using physiological and subjective measures of sexual…
31-3-2014 Hypothesis: Early administration of 5 mg of Metoprolol is associated with a relative 20% reduction in infarct size as measured by cardiac Troponin-T, a total of 408 patients will be enrolled and randomized. Interventions: 5 mg intravenous…
The internet intervention will enhance empowerment, perceived justice, wellbeing and knowledge of personal injury victims during claims settlement.
It is predicted that the PDE5 inhibitor vardenafil will reverse memory impairments induced by THC if the latter depend on glutamatergic neurotransmission. It is expected that the cholinesterase inhibitor rivastigmine will reverse THC-induced memory…
5-ASA and UDCA have a chemopreventive potential in UC.
To determine whether a second IVIg course in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, mechanical ventilation, length of hospital and ICU…
HIV-induced immune activation through intestinal bacterial translocation can be modulated by statins.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
Is the application of CryoSeal (CS) by primary total knee replacement surgery beneficial for the patient with respect to a faster track and improved early (2 and 6 weeks) postoperative rehabilitation as determined by improved knee extension.
Postprandial hyperglycemia has a negative effect on aortic elasticity in patients with impaired fasting glucose versus matched controls.
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…