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Topiramate leads to reduced olanzapine-induced weight gain and calory intake .
For women with a singleton at term fetus in breech presentation, what is the success rate of external cephalic version (ECV) with a calcium antagonist nifedipine compared to version without medication?
Lipolysis inhibition during endurance exercise leads to a significantly greater improvement in 24-hour glycemic control in type 2 diabetes, as opposed to endurance exercise under normal circumstances.
We expect an incidence of delirium in our control group of 30%. This is based on literature documenting incidence of delirium in neurosurgical patients in a northern European population of 29-33%. The expected effect cannot be based on previous…
Oral exposure time and energy content of the gastric load both affect subjective feelings of satiety and gastric emptying rate. It is expected that a longer oral exposure time and a higher gastric energy content would both increase subjective…
Administration of brimonidine eye drops in patients with AION reduces loss of vision.
This present study is a pharmacodynamic study of which the main goal is to confirm the lack of effect of testosterone sublingual alone in 16 premenopausal sexually dysfunctional healthy women using physiological and subjective measures of sexual…
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
Recurrent respiratory tract infections (RTIs) affect 15-20% of children aged 0-5 years and cause high disease burden, frequent doctor visits and are one of the main reasons for hospital admission in childhood. Despite the common use of co-…
We hypothesized that patients treated with Methotrexate (MTX) will have less duration and less severe arthritis, will not or less evolve into RA, will develop less radiographic progression in joint damage, and are more likely to go into remission.
The present mode of (tonic) SCS is accompanied by paraesthesia in the area of stimulation. Recently, a new mode of SCS has been developed which makes it possible to apply spinal cord stimulation without paraesthesias. This mode is called burst…
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
Phytosphingosine decreases cholesterol levels and improves insulin sensitivity
Prevention of respiratory syncytial virus infection using palivizumab in preterm children with gestational age 32-35 weeks will result in decreased incidence of recurrent episodes of wheeze (post-bronchiolitis wheeze).
Is CD35, CD21, CD55 associated With Exudative Age-Related Macular Degeneration?
A relative reduction of 50% in the occurence of traveller's diarrhoea.
Extension of SAD PK/PD Model, confirmation of SAD PD effects
The efficacy of reflux inhibitors, which block transient lower esophageal sphincter relaxations (TLESRs), to reduce acid and non-acid exposure may be hampered in the presence of a hiatal hernia, as other mechanisms of reflux become more important.
Folate supplementation improves microcirculatory function in subjects susceptible to microcirculatory dysfunction.