33 resultaten
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
In the proposed study we will investigate the effect
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
To evaluate the effectiveness of two well defined probiotic strains, Lactobacillus paracasei LPc-G110 (CCTCC M 2013691) and Lactobacillus plantarum GOS42 (DSM 32131), in strengthening the oral ecosystem.
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis
A single subanesthetic dose of intranasal ketamine is able to diminisch acute suicidal ideation and behaviour, regardless of the underlying diagnosis.
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
In this study we will validate nerve excitability threshold tracking, a measurement technique for neuronal excitability. The placebo-controlled mexiletine and lacosamide administration should inform us about the sensitivity of threshold tracking to…
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.
We hypothesize that TRH effectively antagonize opioid-induced respiratory depression
It is hypothesized that this personally tailored physical activity program (I’M FINE intervention) will be more effective in improving physical fitness and enhance daily activity in individuals with slowly progressive neuromuscular diseases (NMD)…
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
1. An early screening at 1y of corrected age will identify preterm children with an increased risk of developing visual processing dysfunctions 2. Early visual rehabilitation from 1y of corrected age will benefit the visual and neurocognitive…
Recurrent respiratory tract infections (RTIs) affect 15-20% of children aged 0-5 years and cause high disease burden, frequent doctor visits and are one of the main reasons for hospital admission in childhood. Despite the common use of co-…
Music interventions will reduce anxiety and pain in patients undergoing a nuss bar procedure due to pectus excavatum
Compared to placebo treatment with low dose amitriptyline or mirtazapine during 16 weeks will improve subjective insomnia in insomnia disorder patients in general practice.
Effectiveness of Moving Stories, a game-based school program aimed at depression literacy and stigma
Our first hypothesis is that adolescents who’ve participated in the Moving Stories program will have better mental health literacy and fewer stigmas regarding depression than adolescents who have not participated, both at posttest and at three- and…
RTX 1*1000 mg compared to a placebo controlled group leads to a higher proportion of patients in glucocorticoid remission at week 21 in newly diagnosed PMR patients fulfilling the Chuang-criteria