617 resultaten
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
First, it will be investigated which is the best diagnostic tool for imbalance in CP. Second, it will be determined whether balance training can promote balance control in CP, and whether the improvements will be maintained after a follow-up period…
We hypothesize that treatment with peppermint oil will lead to a greater symptom (especially abdominal pain) reduction in IBS patients compared to placebo. This will lead to a higher total percentage of responders (as defined by FDA/EMA…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
Cranberry capsules given peri-operatively reduce the risk of clinical overt urinary tract infection after elective pelvic floor surgery with indwelling catheter postoperatively compared with placebo
The aim of this study is to investigate an abridged version of an online health training, based on cognitive behavioral therapy components, that is focused on the optimization of health. It is expected that this online health training will have a…
To study if a Mediterranean diet (MD) followed by lean donor fecal microbiota transplantation (FMT) has synergistic superior beneficial effects on peripheral insulin sensitivity and (small) intestinal microbiota composition as compared to…
Vaginal atrophy in post-menopausal women results in various vaginal complaints, including dryness. Multi-Gyn LiquiGel is a moisturizing gel with osmo-protectant ingredients. We hypothesize that LiquiGel relieves signs and symptoms of vaginal atrophy…
CONFIRMATORY HYPOTHESIS Our novel cognitive training incorporates several aspects that are expected to increase its effectiveness when compared to traditional Cognitive Bias Modification (CBM). As a confirmatory hypothesis we expect that, as an add-…
We hypothesize that our individual rehabilitation program will be (cost-)effective regarding the primary and secondary health- and work-related outcome measures of work in cancer survivors with an employment contract, compared to care as usual.…
Metformin combined with doxycycline will result in a better improvement in HS severity and the pre-diabetic condition of the patients compared to doxycycline monotherapy.
BCG vaccination may induce (partial) protection against susceptibility to and/or severity of SARS-CoV-2 infection. This will lead to reduced workplace absenteism under health care workers taking care of patients with COVID-19
Our hypothesis is that growth hormone threatment in adults with Prader-Willi Syndrome will improve their metabolic and cardiovascuar health, thereby resulting in a reduced mortality.
Systemic eosinophilic inflammation in airway disease (asthma/COPD/asthma-COPD-overlap-syndrome (ACOS)) is associated with small airway inflammation manifesting in dynamic hyperinflation and specific symptoms, which can be reduced by systemic anti-…
Based on Faber ea. 2006, we expect that the effectiveness of ‘In Balans’ can be replicated and extended in a group of community-dwelling pre-frail and non-frail older adults with an increased risk of falls, with a significant reduction of the number…
It is hypothesized that both caloric restriction and exercise lower tumor tissue protein synthesis rates but that exercise, as opposed to caloric restriction, will prevent a concomitant decline in muscle tissue protein synthesis rates.
Capillary malformations (¡®port-wine stains¡¯) are congenital abnormalities of the capillary vessels of the skin, causing a red or purple color. Laser therapy is currently the only widely accepted treatment option, but treatment response is…
We speculate that the virome composition of the lean donor and the subsequent interaction between phages and bacteria in the recipients are crucial determinants of stability and diversity of gut bacterial composition and glucose metabolism in humans…