576 resultaten
Does a Attention Control Training in patients in the experimental group with a PTSD prior to the TAU lead to a better outcome than in patients in the control group with a PTSD who have received a sham (fake) training prior to the TAU ? This is also…
Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo
We hypothesise that using a continuous subcutaneous glucose monitor during pancreatic surgery, will significantly improve percentage of time spent in glycaemic target range (i.e. glucose ≥ 4 mmol/l and < 10 mmol/l).
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
In the proposed study we will investigate the effect
This study aims to apply state-of-the-art immune tests quantifying the immunosuppressive state in individuals, and the relationship between these pharmacodynamic tests and the pharmacokinetic profile (in whole blood and intracellular) after a single…
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
This study aims to establish a plasmakinetic profile of GABA from tomatoes in healthy men and compare it to the kinetic profile of GABA from a supplement. In addition, the effects of glutamate (precursor of GABA) on the plasma-time curves of GABA…
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
To evaluate the effectiveness of two well defined probiotic strains, Lactobacillus paracasei LPc-G110 (CCTCC M 2013691) and Lactobacillus plantarum GOS42 (DSM 32131), in strengthening the oral ecosystem.
Antimicrobial therapeutic clothing are more effective in reducing the severity of atopic dermatitis than non-antimicrobial therapeutic clothing
It is hypothesized that Ziverel tackles esophageal hypersensitivity by protecting the mucosal barrier function.
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis
A combined tDCS-working memory intervention in healthy military personnel strengthens self-regulation under threat via effects on DLPFC-linked neural activity.
Infant formulae with higher levels of milk fat result in improved microbiota composition as compared to standard formula.
A single subanesthetic dose of intranasal ketamine is able to diminisch acute suicidal ideation and behaviour, regardless of the underlying diagnosis.
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
In this study we will validate nerve excitability threshold tracking, a measurement technique for neuronal excitability. The placebo-controlled mexiletine and lacosamide administration should inform us about the sensitivity of threshold tracking to…
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.