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We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
We expect that metformin in combination with lifestyle interventions reduces Antipsychotic induced Weight Gain compared to placebo in combination with lifestyle interventions.
We hypothesize that methylphenidate improves ADHD manifestations in children and adults with SMS.
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
Oral bisphosphonate supplementation or the MMR vaccine can be used as immune potentiators when simultaneously administered with BCG, to further amplify the BCG-induced trained immunity response and maximize potential protective effects against COVID…
Post-donation iron supplementation will be an effective strategy to enhance the iron status recovery in whole blood donors with low ferritin levels.
Due to its ability to avoid preterm birth, the neurodevelopmental sequelae of preterm birth could also be prevented by progesterone. However, progesterone may also exert direct effects on the fetus’ developing brain.
We hypothesize (hypothalamic) obesity can be treated with GLP-1 analogues in patients with craniopharyngioma.
The main objective of the study is to investigate if positional therapy during sleeping, using the LEFT device, reduces nighttime gastroesophageal reflux symptoms.
Sacroiliac joint infiltration with bupivacaine 0.25% is superior to placebo in reducing post-operative pain.
30% improvement is the minimal effect found in previous microneedling studies, based on this studies we expect to find a 7.5 point improvement on the POSAS total score
In T2DM patients with DKD, an acute oral sodium load results in less renal sodium excretion than in healthy individuals and non-DKD T2DM, which can be restored by administration of a GLP-1 receptor agonist.
More physical activity will increase protein synthesis rates of muscle tissue and will decrease protein synthesis rates of prostate tissue and prostate tumor tissue.
Our hypothesis is that treatment with imatinib results in a reduction of the time to liberation from ventilation and supplemental oxygen and alive in Covid19.
combining a standard DIEP-flap breast reconstruction (BR) with an inguinal lymph node transplant will lead to an improvement of the BCR
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
We hypothesize that long-term continuation of macrolide maintenance therapy after at least 1 year of treatment in COPD patients results in a prolonged time to next exacerbation compared to withdrawal of azithromycin macrolide treatment
It is hypothesized that this mobile intervention will effectively reduce alcohol consumption and binge-drinking frequency.