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It is expected that the experimental, but not the control participants, will show a significant decrease in depressive symptoms and anxiety, and a significant increase in physical activity, pro-social behavior and general mental health.
Significantly more patients will express an overall preference for ICI-P versus ICI-B
The DLBP is superior compared to the DHS in terms of revision surgery, union rate, avascular necrosis, implant related failure, as well as functional outcome.
motivational interviewing can be an effective method to support patients in maken lifestule behavior changes
To investigate whether a strategy of direct stenting without pre-dilatation is associated with a reduced incidence of restenosis at 9 month follow-up angiography, compared to conventional stenting with pre-dilatation or compared to a strategy of…
In the intervention group patients with GI cancer and work-related problems will receive tailored support which will lead to a more successful return to work compared to the control group of patients with GI cancer and work -related problems…
The ADMA-level in hypertensive subjects will be reversely related to the basal blood flow and the endothelial NO-availability in the forearm. Pre-treatment with an angiotensin-II- receptorblocker and/or a statin will decrease the ADMA-levels via…
The mean weight gain of healthy infants receiving the study formula(s) during the first months of life is equivalent to the mean weight gain of healthy infants receiving the control formula(s).
The main aims of the PROHTECT trial are to find out whether the compliance rate of the cervical screening programme can be improved by offering a self-sampling method for collecting cervicovaginal cell material at home for HPV testing, and…
Celecoxib, as a selective COX-2 inhibitor, has in vivo disease modifying activity in addition to its inflammation regulatory properties, in comparison to naproxen as a conventional non-selective NSAID.
A diagnostic strategy starting with bronchoscopic cryobiopsy is associated with a reduced need for chest tube drainage in comparison to a diagnostic strategy with immediate surgical lung biopsy, and is therefore associated with a lower patient- and…
GH treatment of short, small-for-gestational-age children has a beneficial effect on linear growth.
The EMPOWER-GR RCT will test the hypothesis that a combined intervention of RET and protein supplementation with an oral nutritional supplement (ONS) is feasible in sarcopenic geriatric rehabilitation inpatients admitted after a hip fracture and…
Combined treatment (collaborative care + duloxetine) is more effective than mono-treatment (duloxetine or collaborative care + placebo) in depressive symptom reduction on the PHQ as main outcome for patients with MDD and (sub)chronic pain.
Assuming that 80 % of the adolescents have a normal growth hormone secretion when retesting in puberty, we think there is no significant difference in final height between the group that discontinue growth hormone treatment (after a normal test in…
1. Does a tailored multi-component intervention (EXBELT) result in the reduction of belts in nursing homes? 2. Does EXBELT prevent the use of belts in newly admitted residents? 3. Does EXBELT reduce the use of other types of physical restraints? 4…
To determine optimal route of iron supplementation during treatment with non-platinum containing chemotherapy for solid tumors.
It is hypothesized that the lotteries will increase abstinence smoking rates over and above an effective smoking-cessation training program.
By providing more intensive social care to highly vulnerable pregnant women, the mother will be more self-sufficient, experiences less stress and the child will develop better, compared to highly vulnerable pregnant women receiving normal social…
To determine the effectiveness of guided CBT compared to care-as-usual in treating insomnia in the general practice.