555 resultaten
The primary objective of the study is to investigate whether an induced nocebo effect can be effectively reduced by open-label counterconditioning, combined with open-label verbal suggestions, as compared to continued nocebo conditioning and…
The growth-mindset intervention will result in more resilient and motivated learners and better school performance than the control intervention.
observational metrics
In the current study, we will construct utility functions of two opioids, tapentadol and oxycodone, to assess the benefit/harm ratio of these drugs. To that end we will perform a PK PD study in healthy volunteers
Feasibility of new health care model
It is hypothesized that this tailored intervention is effective in cancer patients with an adjustment disorder compared to a waitlist control group, and potentially cost-saving.
We hypothesize that ESD will be associated with longer procedure times but lower costs. For lesions that prove to be benign, we hypothesize that ESD will lead to a higher number of R0 resections and lower recurrence rates, particularly for lesions…
Three new time-limited psychological (TLP) treatments for anorexia nervosa (AN) will much reduce both treatment duration and costs relative to top-clinical care (TCC).
We expect that with a target of 1.5-2.0x baseline aPTT or with LMWH the primary composite endpoint will be reached in 60% of patients compared to 70% in usual care. To show non-inferiority with a significance level (alpha) of 5%, power of 80% and a…
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
- Personalized psychological care is more efficacious than standard, non-personalized psychological treatment in improving functioning of cancer survivors. - Personalized psychological treatment is more efficacious than standard, non-personalized…
The effect on compliance with rehabilitation therapy after trapeziectomy, in patients assessing their possible selves before starting rehabilitation therapy, by evaluating PROMS and compliance. Hypothesis: that patients assessing their possible…
Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
We hypothesis that a switching strategy based on adalimumab concentration is superior to usual care switching in rheumatoid arthritis patients failing adalimumab.
Severity of fear of cancer recurrence (FCR) will reduce more with the current intervention than with usual care
Children in the game-based intervention condition will improve more on reading fluency than those in the standard intervention (TUA) condition.
The removal of intrauterine leiomyomas through transvaginal ultrasound-guided radiofrequency ablation is a clinical- and cost-effective alternative for laparoscopic hysterectomy and tomic myomectomy.
The constructed toolkit will be an acceptable and feasible tool to improve personal continuity for older patients in general practice.
Following Moodbuster Lite with guidance provided by a virtual coach or personalised automated motivational support messages leads to higher adherence rates than following Moodbuster Lite unguided.
Our hypothesis is that adolescents playing the YESS! game will show a larger increase in self-management score during the first year of transition and will have a lower drop-out rate at the adult endocrine outpatient clinic (OPC), compared to…