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The objective is to investigate whether application of a stepwise work-up strategy in primary care patients with uncontrolled hypertension results in better blood pressure control in a cost-effective manner.
To assess the efficacy of a calorie and protein restricted (CRPR) diet for induction of remission in CD.
Patients with obesity face many health issues such as obstructive sleep apnea (OSA). Prevalence of OSA may be as high as 70% in high-risk populations such as morbidly obese patients undergoing bariatric surgery. Although bariatric surgery itself has…
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
The hypothesis is that the 'Shine!' intervention will result in parents having better parenting skills and a higher self-efficacy to twice daily brush their children’s teeth, resulting in better oral hygiene and less dental caries…
Our hypothesis is that preservation of the pectoral fascia may lead to a decreased seroma formation when compared to fascia removal, and has a beneficial effect on breast reconstructive surgery.
Childhood obesity is a serious epidemic in western societies. Parents are considered as a key influence in children’s weight-related behaviors. It is thus not surprising that recent interventions to prevent childhood obesity have increasingly…
The main objective of this study is to compare upper extremity dysfunction (UED) following slender TRPCI using small bore catheters (5F) compared to standard PCI using regular size guiding catheters (6F) and conventional stent techniques at two…
the present study investigates whether a small-scale stay in an enriched green environment in a care center is related to a slower progression of cognitive functions, better mood, less behavioral problems, and a higher quality than if standard care…
HYPOTHESES: We hypothesize that the PAMA condition in comparison to the Usual Care condition will: 2. Lead to more high risk smokers engaging to quit 3. Lead to more informed decision to quit smoking by smoking patients 4. Lead to more evidence…
Inhaled levodopa provides more rapid symptom relief than orally administered levodopa
I) The Multi Component Adherence intervention (MCAI) will improve the (cost-)effectiveness of the treatment for osteoporosis at the Fracture liaison service. II) The MCAI will improve the patient's involvement with the anti-osteoporosis…
We hypothesize that the Armed4stroke program will: 1) Increase patients self-reported level of mobility, measured with the Stroke Impact Scale. 2) Smoothen the transition to patients own home situation, which will shorten the length of stay for…
Several studies have looked into hyperkalemia as adverse drug reaction of co-trimoxazole. Many of these previous studies have shown that co-trimoxazole induced hyperkalemia is a potentially dangerous adverse drug reaction, especially in high-risk…
First, we hypothesize that IHNR will shorten the time to regain (baseline) HRQoL. Second, we hypothesize that the program will enhance the ability to resume work-related and daily activities, and will lead to a reduction in medical consumption (e.…
Self help interventions are useful in preventing work-related fatigue in coach drivers in the peak season.
Targeting a higher SpO2 (95% lower limit) in children with moderate-severe BPD from 36 weeks PMA and onwards, will possibly lead to superior growth of normal lung tissue (assessed indirectly by body weight) at 6 months corrected age, compared to a…
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
It is hypothesized that physical activity will have a positive (dose-response) effect on cognitive control, measured as error processing, response inhibition and interference effect.
As collecting the medication at the pharmacist is a prerequisite for medication adherence, the pharmacist could support the doctor to be more responsive to a clients's non-adherence