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1. SNS is more effective than BOTOX® 100 U as assessed by the difference between treatment groups in the proportion of idiopathic OAB patients with a positive treatment response on the Patient Perception of Bladder Condition (PPBC) at Week 12…
We hypothesis that early surgical intervention results in less pain over the study period and is more cost-effective than the optimal current step-up practice.
Formalization of the current guidelines on VTE treatment duration with VKA, by means of using a VTE recurrence prediction model in patients with venous thrombo-embolism, will optimize its cost-effectiveness compared to care-as-usual. Only patients…
High dose of oral administration of omega-3 fatty acids ameliorates hepatic steatosis and insulin sensitivity in morbidly obese patients undergoing LRYGBP.
Compared to treatment as usual adding direct session feedback in the treatment of a mixed diagnostic group of patients in an acute psychiatric crises improves outcome at symptom level, well being, patients’ satisfaction, and drop out.
Compared to treatment as usual adding a tailored adherence interventions Treatment Adherence Therapy (TAT) for outpatient will schizophrenia will improve medication adherence.
This randomized, controlled, diagnostic, multicenter trial will compare two diagnostic imaging pathways--coronary computed tomography angiography (CCTA) and single photon emission tomography (SPECT) myocardial perfusion imaging (MPI)--to determine…
We expected operation time and blood loss to be lower in the SPPC group. Alignment, in terms of percentages of outliers, was expected to be superior in the SPPC group, compared to the conventional intramedullary alignment technique.
The introduction of a virtual asthma clinic may improve the number of asthma free days in children with asthma while the number of visits to the outpatient clinic is decreased by 50%.
Children who attend day care centres are at increased risk of contracting infectious diseases, notably gastro-intestinal and respiratory infections. These not only cause morbidity in the children but also considerable economic costs because of…
The present study will test the effectiveness of a web-based brief alcohol intervention that is aimed at reducing heavy drinking among adolescents with a low educational background, that is participants of secondary schools (VMBO) and institutions…
What is the effect of the newly developed protocol in knee OA patients and comorbidity (coronary diseases, heart failure, diabetes type 2, obesity, Chronic Obstructive Pulmonary Disease (COPD)) on the outcome physical functioning in comparison to a…
Telephone counseling is effective in aiding smoking cessation. The proportion of successful cessation after 3 months and 12 months will be significantly higher in the intervention condition compared to the control condition. Additionally, children…
Postoperative physiotherapy, after Chevron osteotomy, will promote the function of the first MTP joint, as expressed by a difference in AOFAS hallux score of 10 points, compared to a study group without postoperative physiotherapy, after a six…
It is hypothesized that adding nurse-led self-help to usual care is clinically superior to care as usual alone for preventing recurrence in recurrent depressive disorder. In addition, it is expected that the intervention dominates the comparator…
Implementation of pharmacotherapy audit meetings (PTAMs) using quality circles will increase guideline adherence in nursing homes and result in improved quality of psychotropics-prescription in nursing homes.
Although some symptomatic and prophylactic drugs have shown to be effective in children with primary headaches there is a clear need to evaluate the effectiveness of non-pharmacological treatment options for this condition with minimal or no side…
The stump and the intact leg of patients with a transfemoral amputation or knee disarticulation show an increased somatosensory function to compensate for the loss of sensory afferents associated with the amputation.
The use of platelets in addition to mucosa advancement flap in the treatment of complex peri-anal fistula will reduce the recurrence rate of these fistulas.
Necessity: A study on chronic pain in persons with Down syndrome is clinical relevant for 5 reasons: 1. The neuropathology of Down syndrome without and with dementia affects pain-related gray and white matter, which may alter pain experience; 2. The…