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Because of the high cardiovascular risk profile and functional disabilities of obese long-standing type 2 diabetes patients, therapeutic exercise programs have hardly been evaluated in this subpopulation. The current research proposal aims to…
Training medical specialists in consultation skills focused on MUPS patients improves the specialistic care for these patients in terms of illness worries, course of symptoms and daily functioning and reduces the medical costs for this patient group…
Multidisciplinary, goal-attained and individualized rehabilitation after knee arthroplasty will result in more satisfaction regarding activities (level of activities and overall satisfaction) in younger knee arthroplasty patients (<65 years).
Elaborate training will have a positive longterm effect on the longitudinal measurement properties of the PDASII.
Treatment retention of crack cocaine dependent patients increases when a pharmacological agent is added to standard outpatient psychosocial treatment.
The percentage of curatively treatable metastatic disease after surgery for primary colorectal cancer can be increased by means of optimizing follow-up of colorectal carcinoma. Intensifying the follow-up by increasing frequency of CEA measurements…
Fine motor skills of visually impared children will be slower and less accurate compared to normally sighted peers.
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
We hypothesize that, with increased arm abduction moment loading with a constant exerted abduction force, primary arm moment generators (deltoid muscle) will have a greater increase in activation (EMG) as compared to primary arm/glenohumeral…
We hypothesize that the Ketogenic diet will be cost-effective compared to usual care.
1. Gatekeeper training is effective in enhancing relevant skills 2. Gatekeeper training will diminish rates of (attempted) suicides at regional level 3. The intervention is cost-effective relative to routine medical care
Surgical procedures are accompanied by high levels of distress and pain in the adult as well as the pediatric population. Music interventions have shown to reduce this anxiety and pain in adult populations. In this study, we will investigate the…
At equi-analgesia respiratory depression from oxycodone is manifold greater compared to Tapentadol
The aim of this study is to determine the (cost)effectiveness of a home-based functional training programme as compared to regular physical therapy with regard to the ability to live independently and participation of frail elderly of 75 years and…
The main objective of the present study is to evaluate (cost)effectiveness of Dementia Care Mapping (DCM)intervention in nursing home dementia care by performing a large RCT study.
Healthcare professionals need to encourage physical activity according to the guideline for cardiovascular risk management. Patients with cardiovascular risk factors (abdominal obesity, high blood pressure, low HDL cholesterol, elevated…
In this randomized, single blinded controlled trial, we evaluate the role of ketamine as an analgesic component of procedural sedation. We compare the effects of propofol-ketamine versus propofol-alfentanil and propofol-remifentanil for achieving a…
Delegation of clozapine monitoring tasks to a Nurse Practitioner (condition A) is at least as safe as Treatment As Usual: physicians perform monitoring tasks themselves (condition B).
Assess of the effect of HD colonoscopy alone or when combined with different I-scan functions compared to standard colonoscopy with respect to adenoma detection rate.