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We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
Simplified FLT PET parameter.
It is hypothesized that a flexible stepped care program for depression reduces the incidence of depression, severity of depression and anxiety symptoms and healthcare costs among primary care patients with diabetes type 2 and/or CHD and sub…
To determine whether a second dose of IVIg in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, duration of mechanical ventilation, length of…
Both intervention groups, ‘the stories we live by + counselor’ and ‘the stories we live by + peer contact’, are superior to the control group in terms of clinical outcomes (reduction of depressive symptoms and improvement of positive mental health).
Currently the 3-year disease free survival of patients with locally advanced rectal cancer is about 50%. Current standard treatment for patients at high risk of failing locally and/or systemically includes pre-operative long course radiotherapy (5…
We postulate that exhaled molecular profiling obtained from ‘breathprints’ by electronic nose: 1. Is associated with the level of asthma control and; 2. Is associated with an inflammatory profile in induced sputum and blood in steroiddependent…
1. The intervention 'Happiness Route' is effective in promoting positive mental health in comparison to a control condition that consists of optimized care-as-usual; 2. In comparison to the control condition, the intervention '…
The bioavailability and effectiveness of vitamin K tablets and solution are comparable.
Our first hypothesis is that in the two exisiting case management models, the persons with dementia will have less behaviour and mood problems than persons receiving usual care and informal caregivers experience better mental health compared to…
Despite appropriate antimicrobial therapy and supportive care, septic shock is still a major cause of mortality and morbidity. Within the last decade, a broad body of evidence suggests a potential role for mesenchymal stromal cell (MSC, a…
Fluorescent near-infrared imaging can accurately detect lymph nodes non-invasively during SLN mapping in bladder cancer patients.
1. Intestinal fatty acid binding proteins (FABP) are diagnostic markers for necrotizing enterocolitis (NEC) and possibly also for complicated NEC; 2. The cerebro-splanchnic oxygenation ratio ia a diagnostic marker for NEC and possibly also for…
Objectives: The aim of this study is to investigate the feasibility of a computer-based cognitive training (working memory training) in a relative old and cognitive impaired population of MCI patients. We will examine the effect of this cognitive…
We hypothesize that treatment with collagenase clostridium histolyticum (Xiapex) injections will also be effective and show significant improvement in outcomes for patients with DD with contractures of the thumb and first webspace.
Aim of this project is to improve adherence to lower oxygen targets in ICU patients using a two-phase step-wise implementation strategy. RESEARCH QUESTIONs are: What are the effects of a stepwise implementation strategy, including a computerized…
The main hypothesis is: The Door-to-door social inclusion method is an effective and efficient method to improve the social inclusion of vulnerable people in marginalized groups. This hypothesis is divided in three different hypotheses: 1. 50 % of…
It is hypothesized that in patients with COPD pulmonary rehabilitation will reduce respiratory impairments like dynamic hyperinflation and dyspnea during daily activities compared to control patients. Furthermore, rehabilitation will reduce the…
There will be no issues with regards to tolerance in relation to the switch from the current to the new high energy, nutrient enriched infant formula.