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In the present study we will investigate the efficacy of Lybrido and Lybridos in one group of subjects with FSD using SSRIs in the laboratory and in the domestic setting of these subjects. We will measure subjective, physiological and…
A positive effect of a Growing Up Milk with added prebiotics or prebiotics and LCPUFA on the intestinal microbiota of toddlers.
This present study is a pharmacodynamic study of which the main goal is to confirm the lack of effect of testosterone sublingual alone in 16 premenopausal sexually dysfunctional healthy women using physiological and subjective measures of sexual…
It is hypothesized that the behavioral effect (i.e. slower RT and impaired attention) of a non-sedative antihistamine will be apparent in combination with a Pgp-blocker, but will not be apparent when administered alone. This, because when a non-…
Measuring ER-density with FES-PET can be used as a predictive test to select patients sensitive for estrogen therapy.
Treatment with Nevanac in combination with Pred Forte of Cystoid Macular Edema after phacoemulsification is superior to placebo.
Major depressive disorder (MDD) is projected to rank second on a list of 15 major diseases in terms of burden and is highly recurrent in nature. Accordingly, efforts to reduce the disabling effects of this chronic condition should shift to…
We hypothesize that transfusing red cells with a storage time of 2 to 8 days reduces the incidence of nosocomial pneumonia in ICU patients.
Therapy of psychogenic jerks currently focuses on frequently co-occurring psychiatric disease, but results are poor. In this project, we will study the effect of BoNT on movement disorders of psychogenic origin in a mono centred randomised…
Primary outcome measures: 1. Working Memory (WM) training will lead to an increase of WM capacities; 2. Cognitive flexibility (CogF) training will lead to an increase of CogF capacities; 3. The WM training condition, the CogF training condition and…
Intradiscal Methylene blue injection(IMBI) treatment reduces the pain and improves the patients global perceived effect (PGPE) in patients suffering from chronic axial low back pain from discogenic origin and to prove that IMBI treatment is safe and…
By injection of triamcinolone before dilation we hypothesise that the time to repeat dilation is increased and the total number of dilation sessions is decreased as well.
Ocular surface inflammation plays a pivotal role in dry eye. The hypothesis of this study is that markers of inflammation expressed by conjunctival epithelial cells can be used to study inflammation and that the topical use of an anti-inflammatory…
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
BonT is an effective treatment for psychogenic movement disorders.
In young children after cardiac surgery, negative protein balance can be prevented (balance=0) with high protein intake (5 g/kd/day) compared to normal protein intake (2 gr/kg/d).
Recent data showed for the first time that IgE-ACPA antibodies have a direct biological immune response in mast cells of IgE-ACPA+ RA patients. Subsequently, mast cell targeting agents, such as anti-IgE therapy have rationale for application in RA…
The new tube feed will decrease the incidence of nosocomial infections in critically ill patients compared to an isocaloric control product with similar amounts of protein.
We hypothesize that subjects taking propranolol (1h preoperative and directly postoperative) will report: 1. lower levels of state anxiety 2. lower levels of dental trait anxiety 3. lower levels of aversive traumatic memory 4. lower levels of…