309 resultaten
ARA290 will reduce disease activity in rheumatoid arthritis.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
There are significant differences in the quantitative data for the groups of normally sigthed and visually impaired children older than 6 years. The hypothese is that is also for children from 2 until 6 years.
The TENLEP Trials proposal builds on the findings of the INFIR Cohort Study and the recommendations of the NLR-funded international Workshop on Neuropathology in Leprosy in the Netherlands in 2007. At this workshop, several key research questions…
Based on its general pro-hemostatic potential, prothrombin complex concentrate may be effective in (completely or partially) reversing the anticoagulant effect of the new antithrombotic agents Dabigatran and Rivaroxaban.
MR Elastography can be used as a non-invasive tool to diagnose, stage and monitor liver fibrosis. MR Elastography has a better accuracy than FibroScan for the assessment of intermediate fibrosis stages.
There might be biomarkers in infected synovial tissue which have predicting value on the effectiveness of Abatacept on RA.
Is there some course detectable in the ropivacaine levels in the collected shed blood in patients treated with three single local analgesia shots with ropivacaine after total knee replacement.
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
1. Cancer survivors who received the high-intensity exercise program will have significantly higher muscle strength, cardiopulmonary function, and health-related quality of life after 12 weeks intervention compared to cancer survivors who received…
IMRT treatment planning and irradiation in prone position can reduce the dose to the small bowel.
Parens with psychiatric problems often have parenting problems, in particular when they have to deal with other risk factors for poor parenting like for instance isolation and poverty. This means an enhanced risk for their children on developing…
1. Examine the reproducibility of the non-volitional endurance test in healthy subjects. The hypothesis is that the non-volitional endurance test is reproducible; 2. Comparison of muscle endurance tested at three different stimulation intensities.…
Propofol does not change accuracy of pulse contour cardiac output measurements
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Intra-operatieve fluorescente beeldvorming van schildwachtklieren bij baarmoederhalskankerpatienten.
Fluorescent near-infrared imaging can accurately detect sentinel lymph nodes non-invasively during lymphadenectomy in cervical cancer patients.
We therefore hypothesize that FABP/Claudin levels may be used as a diagnostic tool for the identification of intra-abdominal injury necessitating surgery and as a prognostic marker for the development of SIRS/MOF (and morbidity and mortality) in…
Pelvic floor related symptom and Quality of Life questionnaires (IIQ-7, UDI-6, IIEF-5, PISQ-12, PFIQ-7, PFDI-20, FISI, FIQL) in Dutch are valid instruments, which can be used reliably in daily practice and clinical research.
High-risk human papillomavirus (hr-HPV) DNA testing complementary to current cytology examination (i.e. Pap test) of cervical smears has shown an increased sensitivity and negative predictive value (NPV) for cervical cancer and its precursor lesions…