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1) It is possible to record data delivering insights in the actual performance of activities of daily life using the Interaction system in stroke patients in the home environment. 2) It is expected that standard clinical test scores do not…
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We hypothesize that the SCRIPT2 training will be accepted, and that the subjects will be able to use the SCRIPT2 system independently. Also, subjects will show improved arm and hand function over the six weeks of training.
In a randomized controlled study comparing psychiatric consultation with care as usual by the company physician, patients will improve in the intervention group in terms of duration of sick leave, general functioning and quality of life.
1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…
S(+)-ketamine reduces pain in patients with Complex Regional Pain Syndome type 1 having symptoms shorter than 6 months and longer than 3 years.
Alternative hypothesis is that the HR is 1.28 for relapse free survival for the first 2¾ years.
1. The observation of videos of walking people has a beneficial effect on the amount of physical activity and on physical performance in older adults with dementia 2. The observation of videos of walking people has beneficial effects on cognition…
There are no effective interventions to prevent dehydration of elderly people available. Therefeore the RPHS West-Brabant, together with the Gneral Practice de Keen, decided to develop and analyse the efffect of an education strategy. Besides that…
We hypothesise that the new MRI protocol will be superior to the previous protocol at calculating lung volumes and central airways dimensions, and subsequently improve the detection and quantification of TA in both CF and asthma disease pathologies.
We hypothesize that the application of a leukocyte depletion filter for surgical wound blood will reduce organ damage and coagulation disorders through removal of activated leukocytes and other particles. We expect that the efficacy of a cell saver…
Delivery of a generic MBSR training to patients who visit a memory clinic with cognitive complaints, and who show no clinical signs of a cognitive disorder, is feasible.
Prevention of parastomal hernia with a prosthetic mesh in a laparoscopic constructed end-colostomy .
The use of a low weight polypropylene mesh(PPM) in a sublay position reduce the incidence of parastomal hernia in laparoscopic stoma formation.
The goal of this intervention is: 1. To improve the support for successful social participation for adolescents with a visual impairment 2. To develop Mentor Support for the improvement of social participation in adolescents with visual impairments…
Clinical studies with mitoxantrone and clodronate showed a better pain reduction in patients with prostate cancer. Both in vitro and animal studies have shown that paclitaxel and biphosphonates act synergistically and prevent formation and…
1. The recognition of malnourished inpatients will improve by using the SNAQ malnutrition screening tool at admission; 2. Early recognition and treatment of malnutrition is effective and cost effective.
Tumor response from erlotinib and bevacizumab as first line treatment in advanced NSCLC will result in “non-progressive disease” within 6 weeks in more than 50% of patients.
Mycophenolate mofetil is effective in preventing relapses of the nephrotic syndrome and has less nephrotoxic effects compared to ciclosporine A.
A systems biology approach is an hypothesis free study that looks at multiple layers within one patient (genome, epigenome, proteome, metabolome)
Hard-core smokers are smokers who have been smoking for many years and who do not intend to quit. This makes them vulnerable to disease and death. Since hard-core smokers are unlikely to quit smoking, before aiming at actually quitting, we first…