622 resultaten
ARA290 will reduce disease activity in rheumatoid arthritis.
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
1. Frequency of temper tantrums will decrease; 2. Duration of the temper tantrums will decrease; 3. Intensity of the temper tantrums will decrease.
N/A
The addition of a Functional Capacity Evaluation to a cognitive behavioral intervention will improve work ability, quality of life and self efficacy.
1. Muscle ultrasound is capable to detect dermatomyositis and polymyositis in suspected patients; 2. Muscle ultrasound is capable to detect improvement of structural muscle changes induced by treatment; 3. Muscle ultrasound is capable to detect…
The primary goal of this study is to determine whether it is possible to discontinue treatment with TNF blocking therapy in patients suffering from Rheumatoid Arthritis when the patient has had stable low disease activity.
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
There are significant differences in the quantitative data for the groups of normally sigthed and visually impaired children older than 6 years. The hypothese is that is also for children from 2 until 6 years.
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. (Cost)effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
The TENLEP Trials proposal builds on the findings of the INFIR Cohort Study and the recommendations of the NLR-funded international Workshop on Neuropathology in Leprosy in the Netherlands in 2007. At this workshop, several key research questions…
Increasing kidney function by kidney transplantation might improve the circadian rhythms of melatonin concentration, sleep and 24-hour blood pressure profile.
Based on its general pro-hemostatic potential, prothrombin complex concentrate may be effective in (completely or partially) reversing the anticoagulant effect of the new antithrombotic agents Dabigatran and Rivaroxaban.
In the present proposal we aim to study whether the intrauterine application of hyaloronic acid (Hyalobarrier ® Gel Endo) immediately after curettage, in patients with a recurrent curettage reduces the incidence and severity (ESGE score/…
MR Elastography can be used as a non-invasive tool to diagnose, stage and monitor liver fibrosis. MR Elastography has a better accuracy than FibroScan for the assessment of intermediate fibrosis stages.
1. Participation in an early home-based education programme compared to care as usual will significantly increase knowledge on kidney disease and treatment options, communication on renal replacement options and promote a positive attitude towards…
Nebulizing amoxicillin clavulanic acid is more effective for reaching amoxicillin levels in sputum > MIC90 than amoxicillin clavulanic acid given by oral or intravenous administration.
There might be biomarkers in infected synovial tissue which have predicting value on the effectiveness of Abatacept on RA.
Is there some course detectable in the ropivacaine levels in the collected shed blood in patients treated with three single local analgesia shots with ropivacaine after total knee replacement.