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In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
1) Implementing TIPP will prevent acute emergency room (ER) visits, rehospitalisations and inappropriate referrals 2) Implementing TIPP improves transitional patient safety culture 3) Although TIPP aims at reducing transitional incidents,…
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
Electrical stimulation on the foot and lower leg will increase the blood flow and thereby the amount of oxygen to the skin. Our overall hypothesis is that this will help to reduce the risk of decubitus on the heel. The specific hypothesis for this…
Disturbances in the circadian rhythm could be a possible cause for development of delirium.
Fluorescent near-infrared imaging can accurately detect pancreatic cancer non-invasively during a whipple procedure.
About 25% of patients who suffer from a subarachnoid hemorrhage or intraventricular hemorrhage have a vital indication for an external ventricular or lumbar drain to aleviate the intracranial pressure. About 5-10% of these patients develop a…
AIM: Establish the clinical value of sentinel node biopsy in patients with multiple breast tumors. Investigate if an intratumoral tracer injection in the additional tumors results in visualization of extra sentinel nodes/extra lymphatic drainage…
The aim of this study is to investigate wether a eccentric exercise program is more effective in patients with primary subacromial impingement compared to a conventional exercise program. Several studies about the effect of eccentric training in…
Early detection of problems and adequate coaching of frail elderly people is crucial to prevent unnecessary loss of function, decrease in quality of life, and even death in old age. This is especially true for frail elderly people who are admitted…
In the present study we will investigate the efficacy of Lybrido and Lybridos in one group of subjects with FSD using SSRIs in the laboratory and in the domestic setting of these subjects. We will measure subjective, physiological and…
To examine if neurofeedback (NF), by influencing prefrontal alfa-asymmetry, is an efficacious treatment for major depressive disorder.
To evaluate the usefulness of the VascuLuminator in children that are obtaining a venous cannulation prior to elective non-cardiac surgery.
The present mode of (tonic) SCS is accompanied by paraesthesia in the area of stimulation. Recently, a new mode of SCS has been developed which makes it possible to apply spinal cord stimulation without paraesthesias. This mode is called burst…
A randomized controlled trial to compare the following strategies: two IVM-ICSI cycles or one COH-IVF/ICSI cycle. These strategies are expected to have comparable outcomes for ongoing pregnancy rates and direct costs (treatment costs). IVM is…
Peroperative fluorescent imaging of the bile ducts will improve visibility and results in early identification of the common bile duct and the cystic duct during laparoscopic cholecystectomy in patients at risk for bile duct injury.
The goal of this intervention is: 1. To improve the support for successful social participation for adolescents with a visual impairment 2. To develop Mentor Support for the improvement of social participation in adolescents with visual impairments…
• CT based Signature™ will result in a comparable percentage of prosthesis that is placed correctly (within guidelines of 3 degrees varus and 3 degrees valgus). • CT-based Signature™ will result in a comparable alignment of the prosthesis as…