318 resultaten
The hypothesis is that the Vocational Enablement Protocol (VEP) is effective and cost-effective compared with usual care from a societal perspective.
Is there a group of severe haemophilia patients that can reduce or stop prophylaxis in their 2nd and 3rd decade without an increased risk of bleeding and joint damage?
We hypothesize that the job-specific workers' health surveillance (WHS) increases the preventive actions undertaken by the workers after attending their WHS. Secondary, we hypothesize that based on the job-specific WHS, the occupational…
Culture media used for human IVF induce epigenetic deregulation of imprinted genes in placental and/or fetal tissue, which results in a reduced birth weight.
N/A
Implementation of pharmacotherapy audit meetings (PTAMs) using quality circles will increase guideline adherence in nursing homes and result in improved quality of psychotropics-prescription in nursing homes.
1. What are the normoxic ventilation parameters and systolic PAP in MH patients? 2. What is the influence of hypoxia on the systolic PAP on MH patients?
1. What is the effect of a high (4.0 mg) versus low (0.4 mg) dose of folic acid supplementation from 4 weeks before conception to 12 weeks after conception on the prevalence of folic acid related congenital anomalies? 2. What is the effect of 0.8 mg…
Chewing gum before and directly after colorectal surgery stimulates the autonomic nervous system leading to an antiinflammatory effect.
Efficacy of occlusion therapy initiated in patients with untreated amblyopia between twelve and forty years of age is effective.
N/A
The primary objective is to assess the safety of treatment with escalating dosages of VELCADE in combination with ZARNESTRA in subjects with Intermediate-2 or high risk MDS according to the IPSS classification.
Type 2 diabetes is a major threat to human health. Previous studies suggest an altered circadian rhythm of glucose metabolism, leukocyte clock gene expression and hemostasis in patients with type 2 diabetes, but type 2 diabetes patients have never…
Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic disease of unknown cause. Chronic inflammation leads to bile duct destruction resulting in liver failure. PSC is regarded as an immune dysbalance disease. PSC has a strong…
When conservative treatment fail in patients with tonsil related complaints, a tonsillectomy using the classical dissection technique van be performed. In adults substantial morbidity is reported following classical tonsillectomy under general…
Vitamin D supplementation will improve glycemic control in patients with type 2 diabetes melliuts.
Fluorescent near-infrared imaging can assess tissue perfusion in the area of the anastomosis.
Many individuals with a chronic spinal cord injury show a serious inactive lifestyle, associated with secondary complications (e.g. pressure sores, osteoporosis and metabolic syndrome) and a decreased physical capacity. The purpose of this study is…