124 resultaten
Infliximab counteracts the increased synthesis of tumor necrosis factor alpha (TNF-alpha), after which inflammation will decrease and recovery of the disease occur.
For patients with metastatic or local-regional unresectable esophageal carcinoma there is no alternative treatment. In this trial it is studied whether combination chemotherapy with oxaliplatin and capecitabine prolongs survival and improves quality…
To study the effectivity of different retreatment radiotherapy schedules for painful bone metastases.
The hypothesis is that cummulative doses of 2.5, 5.0 or 7.5 gram methylprednisolone infusions are equally effective in moderately severe Graves' ophthalmopathy, but that the doses differ in the number and severity of side effects.
To compare a surgical procedure (gastrojejunostomy, GJJ) with endoscopical stent placement in patients with malignant gastric outlet obstruction (GOO)
10 Gy additional boost to the tumor bed will yield an increase in local control at 10 years from 88% to 93%, with still acceptable cosmesis.
The effect of the TDM strategies on the viral load in terms of change from baseline (start or switch of therapy) to 96 weeks.
There is a need for assistance by primary care mental health workers in general practice in the Netherlands. General Practitioners (GPs) experience an overload of frequent attenders suffering from (co-morbid) psychological problems. For most GPs…
The hypothesis is that 0.5 g/kg/wk of IvIG is as effective as 1.0 g/kg/wk, in the prevention of ICH in FNAIT.
1. To develop (cost-) effective implementation strategies which are feasible in daily practice; 2. To test the guidelines in a multicentre effectiveness trial; 3. To develop general quality indicators with appropriate measuring tools for diagnostic…
Low molecular weight heparin plus aspirin reduces the recurrence of preeclampsia and/or small for gestational age infants before 34 weeks gestational age in women with documented thrombophilia with a history of preeclampsia and/or small for…
The degree of TH1-skewing by mycobacteria is controlled by NRAMP1 gene polymorphisms and related to the degree of inhibition of TH2-mediated disease.
Due to tumoricidal effect of PDT , it is expected that the central bile ducts remain free from tumor and so better and prolonged drainage can be achieved leading to beter QoL and survival.
A late intensification course (VIMARAM) improves the outcome of infants with acute lymphoblastic leukemia.
MPS I patients can be treated with Aldurazyme safely and effectively.
Enzyme therapy with recombinant human alpha glucosidase results in prolonged survival; improvement or stabilisation of cardiac hypertrophy and function, improvement or stabilisation of pulmonary function and improvement or stabilisation of muscle…
We hypothize that in low risk women amniotomy at home for post term pregnancy will result in more sponteneous birth (defined as labour and birth without any obstetric intervention but amniotomy)resulting in lower costs during birth.
Dose-escalation of paroxetine (up to 50 mg/day) does not increase efficacy of treatment of Major Depressive Disorder in patients who did not respond to a 6 week trial of paroxetine in a standard dose (20 mg/day).
1. In patients with a painful arc, treatment with hyaluronic acid and lidocaine, will give a mean improvement of 70 % of their pain at 26 weeks after start of the treatment with subacromial injection as compared to subacromial injection with a…