Zoeken naar een onderzoek

Drinking Less, Self help for Problem Drinking: randomised clinical trial.

To test the effectiveness of a self help booklet without therapist guidance vis-à-vis a psycho-education brochure for adult problem drinkers in the general population.

Immunity induced by yellow fever vaccination in the elderly (60yrs or older)traveller

The induction of immunity might be slower in older persons than in younger individuals. This could influence the occurence of adverse events induced by the vaccine.

A double blind placebo controlled study on the effect of cerivastatin on the process of atherosclerosis in non-insulin dependent diabetes mellitus (type 2).

To assess the effect of statin therapy on the process of atherosclerosis in type 2 diabetes without manifest cardiovascular disease.

Fluvastatin and bisoprolol for the reduction of perioperative cardiac mortality and morbidity in high-risk patients undergoing non-cardiac surgery.

The general objective of the DECREASE-IV trial is to assess the clinical efficacy of beta-blocker therapy, statin therapy and combination therapy with beta-blockers and statins in patients undergoing major noncardiac surgery.

A Randomised, Double-blind, Controlled Study on the Effect of One Year Administration of a Nutritional Concept on Immunological Status in HIV-1 Positive Adults not on Antiretroviral Therapy

Improving the immunological status of HIV-1 infected adults not on antiretroviral therapy through nutritional support.

The pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care.

Describing the pharmacokinetics of nimodipine, especially the variability of bio-availability orally administred nimdipine.

A study to evaluate the different levels of attention and valence direction for erotic stimuli, in relation to genital and subjective sexual arousal in healthy female subjects and healthy female subjects with Female Sexual Dysfunction.

In the present placebo controlled study we will investigate the influence of valence on attention when viewing visual erotic stimuli. Especially when under the treatment condition of testosterone with sildenafil. In addition, we will investigate the…

Effects of crisis cards/plans for people with psychotic illnesses, facilitated through local patient organisation and through clinician, on the number of crisiscontacts with mental health services and the numer of (cumpulsory) admissions.

N/A

Does booster influenza vaccination improve vaccination efficacy in patients with quiescent systemic lupus erythematosus?

SLE patients show a decreased humoral immune response to influenza vaccination, as compared to healthy controls. Furthermore the use of immunosuppressives is of influence on vaccination immunogenicity, it has been demonstrated that the use of drugs…

A Phase II multicenter study to assess the tolerability and efficacy of the addition of Bevacizumab to standard induction therapy in AML and high risk MDS above 60 years.

The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.

Temperature during orthopedic surgery.

Obtain transient temperature data of the skin, core and wound surface during orthopedic back surgery in order to validate the numerical model of Severens for this type of surgery.

Effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections.

This is a superiority trial testing the hypothesis that adenoidectomy is more effective than a watchful waiting strategy in children with recurrent upper respiratory tract infections.

ETMI vs. standard video endoscopy for the detection of early neoplasia in patients with low-grade dysplasia in a Barrett's esophagus: a multi-center randomized cross-over controlled study

ETMI increases the detection rate of early neoplasia in BE patients with 40% or more compared to standard video endoscopy

Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS).

Thrombus aspiration compared to balloon angioplasty will improve myocardial reperfusion during primary percutaneous coronary intervention.

Gerandomiseerde studie naar de effecten van opereren met LigaSure System op het post-operatief herstel en functioneren van de bekkenbodem na abdominale uterus extirpatie.

Use of vessel sealing reduces postoperative pain and improves postoperative pelvic floor function.

Analyzes of pathogen and host determinants in hospitalized patients with a laboratory confirmed infection caused by Staphylococcus aureus: the PATHOS Study.

To identify candidate antigens for the development of a prophylactic Staphylococcus aureus vaccine by studying expression profiles of host and pathogen determinants during natural infection.

Intramedullary Nailing of Diaphyseal Humeral Fractures - T2™ Humeral Nail versus Fixion ® Intramedullary Humeral Nail

Theoretically there are many advantages of using the Fixion ® IM Humeral nail, like a significant reduced surgical and fluoroscopic exposure time. The procedure is simple and minimal invasive. No interlocking screws are needed, thus there is a…

Diagnosis of cystic fibrosis fat malabsorption: fat absorption test.

The double labeled triglyceride and free fatty acid fat absorption test is as effective as the fecal fat balance as a quantitative diagnostic test for intestinal fat absorption in CF patients.

Endometrial aspiration before or after Saline Infusion Sonography (SIS) in case of abnormal uterine bleeding; effect on specimen quality.

The specimen contains less evaluable endometrium after SIS than before SIS.

Small scale living facilities for older people with dementia.

It is hypothesized that residents in small scale living facilities, compared to those in regular nursing home care, have a higher quality of life and functioning. In addition, it is hypothesized that their family caregivers experience less burden…