197 resultaten
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
With implementation of the AWR we expect a reduction in the total amount of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and a total amount of cost savings…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
The overall aim of this proposed study is to gain insight into the target attainment of the administered antibiotics during the two-stage arthroplasty exchange, in order to determine the efficacy in relation to the minimal inhibitory concentration (…
We expect that the access-related intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than by asymptomatic flow reduction detected by…
Children aged 4 to 6 years in the intervention group who have received the GigaGaaf! intervention have a different oral health than children aged 4 to 6 years from the control group who have received care as usual. Parents of the children aged 4 to…
Not applicable
We hypothesize more than 90% of the participants in the in-hospital, standard-of-care follow-up will contact the hospital during the study period and 40-50% of the patients in the patient-led, home-based follow-up will contact the hospital between…
It is hypothesized that in a primary health care population, a more condensed form of schema therapy (ST) might be sufficient for an effective reduction of personality problems.
The course of resting energy expenditure (REE), measured by indirect calorimetry changes based on standard versus high enteral protein feeding in the ICU.
Monitoring a patient’s oxygen status during anesthesia using pulse oximetry is essential. The new Oxygen Reserve Index (ORI) may help provide clinicians real-time visibility to oxygenation in a moderate hypoxic range and serve as a warning of an…
Aim of the study is to determine how often muscle strength measurements should be repeated, using a hand-held dynamometer to obtain a maximal muscle strength measurement
Acute complex skin defects will heal using a dermal substitute (Glyaderm).
The school-based sleep intervention is effective in improving self-reported sleep quality.
Delegation of clozapine monitoring tasks to a Nurse Practitioner (condition A) is at least as safe as Treatment As Usual: physicians perform monitoring tasks themselves (condition B).
Painreduction for 67% of patients with a locally advanced or local recurrent pancreatic carcinoma through a short radiotherapy scheme (single arm phase 2 study)