116 resultaten
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
A combination therapy (MDT and TESIs) is effective and cost-effective compared to usual care among herniated nucleus pulpos patients with an indication for a lumbar herniated disc surgery
Trends in and variability of vital signs reveal hidden information about the state and deterioration of the patient compared to absolute values of vital signs.
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
The Untire app will create awareness by proving psycho-education and will give insight in ones’ energy levels, ones’ thoughts and behaviors in relation to energy levels and provides exercises that help users to challenge ineffective thoughts and…
We believe that by engaging the target group in the process of intervention development, more effective intervention targeting children’s physical activity and dietary behaviors can be developed.
This overall study aims to evaluate the effects of cardiology PC+ centre on the Triple Aim outcomes. The underlying premises of the researchers on the effects of the intervention are that the cardiology PC+ centre will result in an (at least)…
The manual knee-rotation-test in 90 degree flection is reliable
To investigate the possibility to predict chemotherapy response using proliferation assays.
With help of the TOF watch, a reduction in muscle relaxation can be observed earlier. In this way, peroperative events (pain or contractions by the patient) can be prevented. Less peroperative events lead to less postoperative pain.
Patients that receive breast conerserving therapy due to breastcancer with an oncoplastic reconstruction by the plastic surgery are more satisfied with their breast compared to patients receiving breast conserving therapy without a reconstruction.
Persons with intellectual disabilities remain dependent on a caregiver for various aspects of their life, often including coping with emotions and stress. It is therefore crucial that parents and other caregivers of persons with ID are aware of…
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral teacher training techniques for teachers of children attending regular primary school (class 3 to 8, six to thirteen years old) with (…
The new interdisciplinary protocol will attract attention to these cases of hand injuries and patients will get a chance of a better coordinated treatment at the early rehabilitation phase. To restore early function of the hand proper instructions…