5607 resultaten
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
Structured cultural sensitive pre-Ramadan education helps people with diabetes who choose to participate in Ramadan fasting to experience a safer Ramadan period. Pre-Ramadan education reduces the risk of acute complications such as hypoglycemia. The…
1) It is possible to record data delivering insights in the actual performance of activities of daily life using the Interaction system in stroke patients in the home environment. 2) It is expected that standard clinical test scores do not…
Intravenous ketamine infusion will result in analgesia
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The hypothesis of the present study is to demonstrate that detection of a particular pattern (e.g., persistent vs. non-persistent) of myocardial (alpha)V(beta)3/5 expression by scintigraphy imaging at 3 and 8 weeks after MI can be used to determine…
Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
ARA290 will reduce disease activity in rheumatoid arthritis.
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
The null-hypothesis predicts that Inlife is not feasible. The alternative hypothesis predicts that the Inlife intervention is evaluated as being feasible. We expect the alternative hypothesis to be true. Inlife will be feasible and minor revisions…
1) The knowledge of the legal aspects of health care and medical negligence/errors among medical residents is larger in the intervention group than for the control group 2) The flipped classroom model is effective as a teaching method in post…
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
We hypothesize that the SCRIPT2 training will be accepted, and that the subjects will be able to use the SCRIPT2 system independently. Also, subjects will show improved arm and hand function over the six weeks of training.
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
The hypothesis of this study is that a difference in mental well-being can be observed after insertion of an LNG-IUD compared to Cu-IUD insertion.
Therapeutic footwear of which adequate off-loading properties are guaranteed and monitored by dynamic plantar pressure assessment will result in a reduced plantar re-ulceration rate in diabetic patients with prior plantar foot ulceration compared to…
In a randomized controlled study comparing psychiatric consultation with care as usual by the company physician, patients will improve in the intervention group in terms of duration of sick leave, general functioning and quality of life.
1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…