960 resultaten
Elevated levels of Free Fatty Acids during fasting induce oxidative stress and cause insulin resistance to maintain euglycemia.
Due to the increased use of CFR PEEK implants and the potential benefits of CFR PEEK over metal we propose to evaluate the safety and effectiveness of CFR PEEK implants in patients with bone tumors in this international multicenter retrospective…
Evaluation of fertility care in the Princess Maxima Center: It is feasible to identify, assess on risk and inform all girls newly diagnosed with cancer, offer additional counseling for patients at increased risk for infertility and safely offer…
The objective of this study is to measure the effect of ‘the healthy worksite cafeteria’ on eating behavior of visitors in Dutch worksite cafeterias. It is hypothesized that the intervention will result in an increase in sales of fruit and…
We hypothesize that surgical patients in the new cohort have poorer health conditions prior to surgery and poorer health outcomes post-surgically compared to the control cohort (TRACE study)
We hypothesize that the HINTS+ test is more reliable than early MRI imaging in patients with acute onset continuous dizziness. As a result it is hypothesized that HINTS+ clinical examination leads to lower costs and an improvement in Quality of Life…
The succesful implementation of shared decision making, supported by outcome measures, for treatment modality decisions in advanced kidney disease facilitates and improves this decisional process and the quality of delivered healthcare.
The hypothesis is that an increased level of dysfunctional modes at baseline predicts lower CBT success (i.e., smaller reduction of symptoms). The second hypothesis is that an increased level of healthy modes at baseline predicts higher CBT success…
There is no difference in survival between indirect and direct composite restorations after 10 years.
The purpose of the Liberté One study is to assess procedural, clinical and angiographic outcomes of the provisional T-stenting approach with the Taxus Liberte stent implanted in complex lesions (with side branch involvement). The Taxus Liberte stent…
The nephrotoxicity caused by cisplatin is of great concern both in that it is dose-limiting and can be detrimental to the patient. Much work has been done to reduce or prevent this damage to renal cells, however to date the best approach has reduced…
A health education program for both patients and general practitioners will change behaviour by 15%.
Recurrent ventricular tachycardia (VT) is an important cause for mortality and morbidity in patients with left dominant non ischemic cardiomyopathy (NICM). Since implantable cardioverter defibrillators (ICDs) may only terminate and not prevent…
An expectative management ('watchful waiting') is not inferior regarding the composite of mortality and/or necrotising enterocolitis and/or bronchopulmonary dysplasia in comparison with an early treatment regime in preterm infants with a…
The dutch language version of the PRHWE and the Quick DASH questionnaire are valid to use in patients with hand and wrist complaints
Higher concentration nintedanib in normal lung tissue compared to fibrotic lung tissue.
The absolute bioavailability of oral imatinib (Glivec®) at steady state can be calculated using LC-MS/MS after concomitant administration of a single 100 µg microdose of stable isotope labeled imatinib (imatinib-d8).
Patients undergoing superior capsule reconstructions (SCR) for superior shoulder instability will experience less pain (decrease of at least 2 points) and improved function.
Both surgical interventions have impact on the quality of life