3254 resultaten
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
Patients could be stratified into a high-risk or a low-risk group so surveillance intervals can be tailored and the clinical and economic burden of endoscopic surveillance can be reduced.
There is considerable interlaboratory variation in the grading of dysplasia in duodenal adenomas.
We hypothesize that patients with symptoms of inability to belch have ineffective UES relaxation in response to esophageal distention caused by air.
Care workers and clients allocated to the intervention arm (receiving access to the ZELF program) will improve their 'stimulation behavior' and 'optimize function' respectively.
The flavonoid-drug interaction could potentially lead to higher nintedanib absorption by the gastro-intestinal tract. This would cause higher systemic bioavailability and lower local gastro-intestinal drug concentrations. Furthermore, inter-patient…
Primary Objective: The main study parameter is to establish the safety of the use of IXSI in an interventional setting. Safety will be assessed based on the CTCAE methodology. Use of IXSI will be considered safe in the absence of Adverse Device…
We hypothesize that frailty in older individuals might underly low responses to the 23-valent polysaccharide pneumococcal vaccination (PPV23) that will be implemented in the National immunization program in autumn this year for elderly 73-79 years…
Data on these complications vary. Since this is an observational study, we are interested in overall incidence and prevalence. Therefore we do not have a clear hypothesis.
Use of videoconsultation and online educational videos can reduce postCABG care consumption with the first 30 days and improve patient quality of life and recovery.
Severe SARS-CoV-2 infection (admitted patients) have significant burden of long-term sequelae: inflammatory response, functional decline, pulmonary fibrosis, lung function abnormalities, cardiac dysfunction and/or psychological sequelae
We hypothesize that there is no difference in clinical and radiological outcome when using PSG for UKA compared with results from the literature describing results from conventional UKA surgical techniques.
It is hypothesized that the FitMáx© questionnaire is a valid clinical assessment tool for CRF compared to the gold standard, a cardiopulmonary exercise test. Moreover we believe the FitMáx© to be fairly accurate in the preoperative risk assessment…
The aim of this study is to develop and evaluate a health behavior change and social network enhancement intervention for low-income households in Apeldoorn who receive care for multiple problems (such as financial debts, domestic violence,…
screening for cardiovascular diseases will reduce coronary heart disease-related mortality and morbidity
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
A combination therapy (MDT and TESIs) is effective and cost-effective compared to usual care among herniated nucleus pulpos patients with an indication for a lumbar herniated disc surgery
We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…