8 resultaten
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
Treating a symptomatic urinary tract infection in patients with a long-term indwelling catheter for 5 days is non-inferior compared to the standard duration of 10 days of antibiotic therapy with regard to clinical cure rate.
Preventive group support for 6 to 8 years old children after parental divorce or separation, leads to: - more positive child functioning; - decreased emotional and behavioral problems of participating children; and - increased child wellbeing;
1) Surveillance of patients with a urine test, followed by cystoscopy only when the urine test is positive, results in detection of a the same or a higher number of recurrences and is cost-effective and 2) urine diagnostics contribute to earlier…
1. Which factors influence electronic cigarette use?
The majority of adolescents in the Netherlands has an inadequate consumption of fruit, vegetables, fibers and an excessive consumption of energy-dense, nutrition-poor foods. Unhealthy diets result in an increased risk of overweight, obesity and…
A disease control of 60% is expected and will be clinically relevant with a lower reference bound of 45%.
The aim of the study is to examine the effectiveness of Rock and Water (R&W) and possible moderators and mediators. Effectiveness: - The R&W program will increase students’ socio-emotional adjustment (i.e., psychosocial wellbeing,…