7151 resultaten
DBS-related cognitive decline and psychiatric side-effects in Parkinson's disease (PD) patients can be studied from a functional- and structural network point of view. We will characterize functional and structural brain networks in PD patients…
Does sildenafil improve tumour perfusion?
We hypothesize that selfmanagement support via an internet based service in addition to usual care will improve health related quality of life in patients with severe asthma who have participated pulmonary rehabilitation in specialized asthma…
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
The main objective of this study is to compare upper extremity dysfunction (UED) following slender TRPCI using small bore catheters (5F) compared to standard PCI using regular size guiding catheters (6F) and conventional stent techniques at two…
DOACs are non-inferior to LMWH with regard to the risk of ICH in patients with brain cancer requiring anticoagulation.
We hypothesize that, with increased arm abduction moment loading with a constant exerted abduction force, primary arm moment generators (deltoid muscle) will have a greater increase in activation (EMG) as compared to primary arm/glenohumeral…
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
The primary hypothesis for this data collection study is that there are various surrogate physiological parameters for inferring blood pressure (BP), which can be more easily obtained than the direct BP measurement. An example of such surrogate…
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
Prevention of the progression of TMD to ML-DS by chemotherapeutical profylaxis can be possible.
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
Intravesical instillation of BCG is a widely accepted strategy to prevent recurrence of non muscle invasive bladder cancer. The most accepted treatment schedule is induction of BCG: weeks 1 through 6 plus maintenance (weeks 1,2,3) at months 3,6 and…
Radium-223 is the 5th treatment for metastasized castration resistant prostate cancer with a proven overall survival benefit. The improved survival of Radium-223 over placebo was demonstrated in the ALSYMPCA trial, which included a miscellaneous…
Determine whether fast track perioperative care program is preferred above standard perioperative care program in hand-assisted laparoscopic donornephrectomy.
It is hypothesized that a multifaceted implementation strategy compared to a minimal implementation strategy will be more effective to implement the Participatory Approach (PA) within a company. A tailored training for supervisors in applying the PA…
To elongate the service life of the implantable neurostimulator while achieving a minimal improvement of 50% of the symptoms of overactive bladder compared to baseline.