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RAR-CLA and cognition

Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo

The surplus value of Doppler in Hemorrhoid Artery Ligation procedure.

Standard localized ligations are as feasible as doppler-guided ligations of hemorrhoid arteries.

Safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) study with ENX-201

A relationship exists between a pharmacologic effect of ENX-201 and the plasma concentration

Active plus: implementation and evaluation of two tailored physical activity interventions among the over-fifties.

1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…

Reducing primary and secondary cesarean delivery rates in women with a previous cesarean delivery using electrohysterography: randomized controlled trial

We hypothesize that the percentage of successful TOL will increase with the use of EHG because EHG provides more accurate assessment of UA, allowing for better optimization of the contraction pattern during labor. Besides, more reliable monitoring…

Assessment of Perinatal Outcome by uSe of Tocolysis in Early Labour: Nifedipine versus placebo in the treatment of preterm premature rupture of membranes.

The aim of the study is to assess whether in women with early PPROM tocolytics improve perinatal outcome.

Effect of a new synbiotic mixture of short chain galacto-oligosaccharides, long chain fructo-oligosaccharides and Bifidobacterium strain on the gut microbiota of caesarean delivered infants.

The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.

The management of actinic keratosis in transplant recipients.

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Dyspepsia - Amitriptyline.

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The Most Effective Treatment Strategy for Diabetic Macular Edema.

Combined (repeated) laser photocoagulation prolongs time to failure compared to anti-VEGF monotherapy.

Cardiac effects of high thoracic epidural anaesthesia during bicycle exercise: an echocardiographic study

We hypothesize that the circulatory and cardiac effects of TEA will be most pronounced during circumstances of increased sympathicotonus, which will be induced by an exercise test on a bicycle.

Walking and cognition in older people with dementia

Walking benefits cognition, executive control processes in particular

PACE Plus trial

Low back pain is common and associated with a considerable burden to patients and society. There is uncertainty regarding the relative benefit of Paracetamol and Diclofenac and regarding the additional effect of pain medication compared with advice…

Effect of an exercise program on the jump-landing technique in athletes.

Has a coach supervised intervention program targeting jump-landing technique effect on the incidence of lower extremity injuries.

Hypoallergenicity of an extensively hydrolyzed whey protein infant formula in children with cow's milk allergy.

The formula will be tolerated by at least 90% of the children with cow's milk allergy with a confidence interval of 95%.

A prospective double-blind multi-centre trial: Laparoscopic versus open elective sigmoid resection in patients with symptomatic diverticulitis (Sigma-trial).

That the laparoscopic approach should be preferred over the open procedure in cases of an elective sigmoid resection for symptomatic diverticulitis.

Clinical study to evaluate the safety and efficacy of recMAGE-A3 in patients from which the bladder is removed due to muscle invasive bladder cancer.

The disease free survival will be prolonged in MAGE-A3 positive patients treated with recMAGE-A3.

Body composition and colorectal cancer recurrence and survival

There are three main hypotheses: 1.visceral adiposity is associated with increased risk of recurrence and with decreased survival, 2.indicators of low muscle quality (low muscle mass, low muscle attenuation and increased inter-muscular fat areas)…

The effects of propranolol on fear of wisdom tooth removal: A randomized, placebo-controlled, double-blind, parallel design trial

We hypothesize that subjects taking propranolol (1h preoperative and directly postoperative) will report: 1. lower levels of state anxiety 2. lower levels of dental trait anxiety 3. lower levels of aversive traumatic memory 4. lower levels of…

A phase II, randomized, single-blind study to investigate the safety and efficacy of 3 dosing regimens of ABP-700 for procedural sedation in adult patients undergoing colonoscopy.

Phase I testing of ABP-700 alone and with remifentanil co-infusions have shown the ability to produce consistent dose dependent sedation effects with conditions favorable for procedural care including minimal involuntary muscle movement, stable…