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We hypothesize that autotransfusion of leukocytes and lipid depleted cell saver blood leads to less prone inflammation and coagulopathy after cardiac surgery. We expect a less activated (cell derived-microparticle poor) and a more ‘pure’ (hemolysis…
Our primary outcome is change in suicide ideation in patients. We hypothesise that, as a result of the improved skills and confidence of healthcare professionals in the experimental condition due to the intervention, suicidal patients are better…
We hypothesize that exogenous, enterally provided glutamine contributes substantially to the de novo synthesis of arginine in surgical patients. We hypothesize that aortic replacement surgery contributes to an alteration in arginine metabolism by…
A combined physical and face-name training is more effective on cognitive outcomes than the treatments separately.
This study will test the hypothesis that acute preoperative administration of statins will offer a better protection against MIRI than long term preoperative administration does.
Children in the intervention conditions will be more likely to have negative attitudes and norms towards smoking and alcohol than children in the control condition.
We aim to compare the effectiveness, feasibility and safety of both metformin and sitagliptin in patients with TIA or minor ischemic stroke and impaired glucose tolerance. We will assess whether a slow increase in dose of metformin and better…
Our hypothesis is that there is no difference in outcome between patients having their incompetent GSV treated with ClariVein therapy using Polidocanol 2%, 3% liquid or 1% foam.
The objective of this study is to support consumers in their decision whether they want to perform a self-test or not. By providing objective information on self-testing, we expect knowledge levels of participants who have viewed the decision aid to…
In patients with irreversible corneal endothelial failure, corneal transplantation is the only effective treatment. Currently, the predominant transplantation technique for patients with corneal endothelial disease is Descemet Stripping Automated…
Parents will improve their communication- and education skills about alcohol-, tobacco-, and cannabis use.
Is there a group of severe haemophilia patients that can reduce or stop prophylaxis in their 2nd and 3rd decade without an increased risk of bleeding and joint damage?
Gastric feeding, in an intact GI tract, will initiate a more physiological response than jejunal feeding.
We hypothesize that the response of the bronchial mucosa to nanoparticles is a critical determinant of their pathophysiological effects in humans in vivo. More specifically, we postulate that carbon nanoparticles cause dose-dependent local and…
Intervention group will show more improvement on substance use and trauma-related symptoms than control group.
We expect a higher functional level (Harris hip score) 6 weeks and one year after total hip replacement.
The purpose is to evaluate the effectivity of participation experienced by representators of palliative care-users in the six Networks Palliative Care on matters of content and decision making process of the Networks. And to make improvement…
In this study we investigate the effect of ketamine on the brain. We hypothesize that ketamine influences brain areas involved in pain, cognitive function and psychosis. The study aims are: 1. To investigate the effects of 2 plasma levels of S(+)-…
Symptomatic postpartum urinary retention (PUR) is a common complication with a varying prevalence, from 0.5 – 18%. Women who are diagnosed with symptomatic PUR are unable to void within 6 hours after the delivery or have clinical signs of a bladder…
Selection of the best embryo for transfer is the key to achieve high implantation rates and is still largely based on morphological assessments at fixed time points. Newly emerging techniques, enabling safe time-lapse photography of embryo…