34 resultaten
In this protocol we will study the value of selinexor as the third agent based on its unique mechanism of action and reported synergy with bortezomib in patients with progressive or refractory MM.
A nutrient rich diet can improve immunological functions and reduce respiratory infections
The hypothesis is that adding ablations of complex fractionated atrial electrograms (CFAE) in a restricted area of the left atrium to pulmonary vein antrum isolation (PVAI) in patients suffering from (longstanding) persistent atrial fibrillation, is…
Using mental imagery, the intermanual transfer training for prosthetic users can be improved.
The hypothesis is that less calories are purchased in the food tax conditions compared to the control condition
The main aim is to evaluate the effectiveness of a blended behavioral activation intervention or the offering of psychological care using an e-health program blended with support offered by the mental health worker of the general practice (in Dutch…
Public health nurses who are trained in providing oral health advices and in inpecting the mouth reduce the prevalence of ECC more than nurses that are not trained.
It is hypothesized that both surgical techniques do not make more than 10 points difference in the American Orthopaedic Foot and Ankle Society (AOFAS) lesser toe metatarsophalangeal scale, one year after surgery.
Huntington’s Disease (HD) is a progressive, neurodegenerative, autosomal dominant disease characterized by motor - and psychiatric disturbances, and cognitive decline. These changes often result in decline of the expressive and communicative skills…
The Versascope (3.5-5.3mm diameter) induces less pain than a conventional hysteroscope (5.5mm diameter) during a hysteroscopic procedure in an office setting.
Liver transplantation with a donor organ from a donation after circulatory death (DCD donor, carries a much higher risk on biliary complications, with subsequently increased risk for decreased graft survival and need for re-transplantation.…
We hypothesize that propofol combined with ketamine has a optimal physician’s satisfaction, patient’s satisfaction and hemodynamic stability, in comparison with propofol combined with either alfentanil or remifentanil.
This trial aims to evaluate the effects of two computer-tailored print-delivered interventions aimed at improving dietary and PA behavior among adult Dutch, Turkish and Moroccan LSES women. One intervention is tailored to cognitive variables (…
• Participants in the experimental condition (i.e., mindfulness exercises) will experience a larger decrease on the implicit negative affect scale of the Implicit Positive and Negative Affect Test compared to the waitlist condition • Participants…
We hypothesize this difference is due to differences in the mechanisms by which the individuals can withstand and/or adapt to the stress conditions applied in the clinical model and that these mechanisms are of key importance in our ability to…
Patients with SIS treated with bursectomy in combination with acromioplasty have higher mid-term Constant scores than patients treated with bursectomie alone.
We hypothesize a lung–protective mechanical ventilation using lower tidal volumes during general anesthesia for minimally invasive transthoracic esophagectomy to protect against postoperative pulmonary complications in patients undergoing minimally…
The overall aim of this study is to study the effectiveness of a PLISSIT-model intervention in men and women with type 2 diabetes in primary care. Primary outcomes include sexual functioning, sexual satisfaction, and quality of life. Secondary…
We hypothesize that adaptation or tuning of the population PKPD model of propofol will decrease the residual error between predicted and measured plasma-concentrations during maintenance of anaesthesia. The adapted PKPD models can also be used…
Can IMT and Distension measurment of the iliacal artery determine Endofibrosis in an early stage and is there a link between the development of endofibrosis and the coagulation activation potential of the blood?