175 resultaten
In the RIO study programme, the efficacy of rimonabant was examined. The next step is to assess the use of rimonabant, its safety and effectiveness in daily practice. In daily practice people also have other diseases, may use other medication and…
Several open-label pilot studies have shown a promising effect of intrapyloric botulinum toxin injection on symptoms in severe gastroparesis. However, data from randomized, double-blind, placebo-controlled studies are not yet available. We intend to…
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
DBS in the nucleus accumbens can lead to long-term improvement of obsessive-compulsive symptoms and funtioning, without unacceptable side-effects.
1. In the first intervention group, the % of subjects who meet the national physical activity guideline will significantly increase; 2. In the second intervention group the % of subjects who meet the national physical activity guideline will…
Dietary intervention using the food for special medical purposes in question to address specific nutrient deficiencies has a positive effect on cognitive performance in patients with early Alzheimer’s Disease.
Improvement of the intestinal microflora of children consuming a fibre-enriched versus a standard paediatric tube feed.
RhDNase can liquefy mucus in children with an atelectasis during mechanical ventilation, resulting in improved mucociliary clearance, less mucus retention and less airways obstruction, thereby enhancing the rate of resolution of an atelectasis.…
rhDNase improves lung function in children with persistent asthma who have persistent obstructive pulmonary function; Treatment of mucus impaction is an interesting alternative approach to treat peripheral airflow limitation in asthmatic patients.…
Based on systematic reviews concerning effective treatments in children with migraine a medical treatment (propanolol) as well as a non-medical treatment (relaxation therapy) appear to be effective compared to no treatment or placebo. however their…
Aetiology of late-onset depressive spectrum disorders may be different from the aetiology of early-onset depression. Concordant with the supposed aetiology of dementia, it has been postulated that chronic low grade immune activation plays a role in…
Our hypothesis is that peroperative fluid restriction will lead to a significant reduction of solid phase gastric emptying time ¨C measured by radionuclide scintigraphy-, and a reduction in its related postoperative complications.
1. Imipramine and Venlafaxine are comparable in efficacy in inpatients with a major depression; 2. Imipramine and Venlafaxine are comparable in tolerability; 3. Patients with a Venlafaxine plasma level < 195 µg/L show comparable…
Usage of disease specific tube feed will improve glucose control in diabetic patients.
Imiquimod, an immunomodulator, has been shown safe and effective in the treatment of external genital warts caused by low risk human papillomavirus (HPV). Therefore, it is hypothesized that this topical treatment may also be effective against…
T-cell inhibition with Mycophenolate Mofetil (MMF) attenuates T-cell number, T-cell activation and T-cell – monocyte interaction, thereby minimizing the T-cell-driven inflammatory amplification loop. The latter will contribute to improvement of anti…
Bipolar devices will minimize the disadvantages of the monopolar device; risk of electrolyte disturbances by using saline irrigation, bleeding and the risk of nervous stimulation
Adjuvant intra-articular corticosteroids reduce the clinical signs and symptoms of bacterial arthritis and improve outcome.
To determine the effect on HbA1c of a disease-specific enteral formula compared to an isocaloric standard enteral formula (control) in type 2 diabetic patients after 12 weeks of supplementation.
Cholesterol lowering by low fat diet and lovastatin will also reduce very long chain fatty acids in patients with X-ALD.