48 resultaten
Low-load blood flow restriction therapy has beneficial effects on postoperative quadriceps and hamstrings atrophy/strength, at 8 and 14 weeks after bone-patellar tendon-bone anterior cruciate ligament reconstruction, compared to standard care…
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
1) It is expected that the percentage of days abstinent will be higher in both training interventions compared to the sham ApBM with religion-adapted ApBM having the biggest effect-size in this comparison. Also, it is expected that participants with…
We hypothesize that among breast cancer patients with a grade 3 breast fibrosis the RILA frequency is significantly lower compared to the RILA frequency among breast cancer patients with no fibrosis.
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
The study hypothesis is that the LSD group shows an increase in positive mood and subjective effects between baseline and follow-up after 4 weeks of repeated dosing with LSD compared to the placebo group. An additional study parameter is the…
We hypothesize that consumption of mixtures of 400 grams vegetables and/or fruits for 2 weeks will result in lower ex-vivo induced oxidative DNA damage, increased antioxidant capacity of blood plasma, reduced levels of reactive oxygen species in…
1. Chronic treatment of 24 weeks with 50 μg roflumilast, compared to placebo, will improve episodic memory in MCI patients 2. Chronic treatment of 24 weeks with 100 μg roflumilast, compared to placebo, will improve episodic memory in MCI patients.
Our hypothesis is that treatment with imatinib results in a reduction of the time to liberation from ventilation and supplemental oxygen and alive in Covid19.
SCFA butyrate supplementation affects blood pressure
Due to the difference in mineralocorticoid characteristics between prednisolone and dexamethasone, it is hypothesized that dexamethasone will have a greater effect then prednisolone, especially when assessing neurocognitive function and blood…
Post-donation iron supplementation will be an effective strategy to enhance the iron status recovery in whole blood donors with low ferritin levels.
Due to its ability to avoid preterm birth, the neurodevelopmental sequelae of preterm birth could also be prevented by progesterone. However, progesterone may also exert direct effects on the fetus’ developing brain.
In T2DM patients with DKD, an acute oral sodium load results in less renal sodium excretion than in healthy individuals and non-DKD T2DM, which can be restored by administration of a GLP-1 receptor agonist.
Does FMT improve residual beta cell function in longstanding DM1
We speculate that the virome composition of the lean donor and the subsequent interaction between phages and bacteria in the recipients are crucial determinants of stability and diversity of gut bacterial composition and glucose metabolism in humans…
Patients supported by the intervention version of the app will report a significantly higher quality of life than cancer patients having a stoma who are supported by the control version of the app.
Deze studie is overgegaan naar CTIS onder nummer 2024-511492-15-00 raadpleeg het CTIS register voor de actuele gegevens. Deel 1: Om de veiligheid en verdraagbaarheid van 2 doses (100 milligram/kilogram [mg/kg] en 200 mg/kg) eteplirsen te evalueren…