354 resultaten
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
We hypothesize that treatment with peppermint oil will lead to a greater symptom (especially abdominal pain) reduction in IBS patients compared to placebo. This will lead to a higher total percentage of responders (as defined by FDA/EMA…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
Cranberry capsules given peri-operatively reduce the risk of clinical overt urinary tract infection after elective pelvic floor surgery with indwelling catheter postoperatively compared with placebo
To study if a Mediterranean diet (MD) followed by lean donor fecal microbiota transplantation (FMT) has synergistic superior beneficial effects on peripheral insulin sensitivity and (small) intestinal microbiota composition as compared to…
Vaginal atrophy in post-menopausal women results in various vaginal complaints, including dryness. Multi-Gyn LiquiGel is a moisturizing gel with osmo-protectant ingredients. We hypothesize that LiquiGel relieves signs and symptoms of vaginal atrophy…
Systemic eosinophilic inflammation in airway disease (asthma/COPD/asthma-COPD-overlap-syndrome (ACOS)) is associated with small airway inflammation manifesting in dynamic hyperinflation and specific symptoms, which can be reduced by systemic anti-…
H1: Exposure to a mode tailored website as compared to exposure to a standardized website will have a positive effect on distress before the consultation (H1a), communication characteristics during consultation (H1b), distress directly after the…
Low back pain is common and associated with a considerable burden to patients and society. There is uncertainty regarding the relative benefit of Paracetamol and Diclofenac and regarding the additional effect of pain medication compared with advice…
Capillary malformations (¡®port-wine stains¡¯) are congenital abnormalities of the capillary vessels of the skin, causing a red or purple color. Laser therapy is currently the only widely accepted treatment option, but treatment response is…
1. Tapentadol produces effective pain relief in low back pain patients 2. Tapentadol treatment improves/enlarges CPM in patients with CPM defects 3. Tapentadol treatment improves/reduces temporal summation 4. Tapentadol is most efficacious in…
In this double-blind randomized placebo-controlled trial, we hypothesize to observe a reduced incidence of antibiotic associated diarrhae (AAD) in inpatients with a spinal cord injury (SCI) during the intake of probiotics, in comparison to a placebo…
Treatment of fear of falling in hip fracture patients in GR, using the FIT-HIP intervention, will lead to reduction of fear of falling and therefore to an improvement of mobility function (gait and balance), in comparison to patients with fear of…
The use of a GDFT protocol during liver surgery instead of the widely used LCVP regimen has no influence on blood loss.
We postulate that faecal microbiota transplantation (FMT) from obese donors in patients with cancer can improve satiety (appetite) and subsequently nutritional status. Secondly, FMT might restore the gut barrier function and hence reduce systemic…
Not applicable
1. Tapentadol produces effective pain relief 2. Tapentadol treatment improves/enlarges CPM resonses 3. Tapentadol treatment improves/reduces temporal summation responses 4. Tapentadol treatment improves/reduces offset analgesia responses 5.…